Serological study of Trypanosoma cruzi, Strongyloides stercoralis, HIV, human T cell lymphotropic virus (HTLV) and syphilis infections in asymptomatic Latin-American immigrants in Spain

Section: Discussioncontrasting

confidence: 53%

Usefulness of the ARCHITECT Chagas^® assay as a single test for the diagnosis of chronic Chagas disease

Pérez‐Ayala

Fradejas

Rebollo

et al. 2018

“…The Egger coefficient was 2.2 (P = 0.016), showing significant risk of publication bias. Thirteen studies including altogether 5366 patients employed an ELISA-based serological test (Table 2) [22][23][24][25][26][27][28][29][30][31][32][33][34] to detect S. stercoralis IgG antibodies. These studies found a prevalence of strongyloidiasis ranging from 5.5% to 26.8%, and of 14% (95%CI 11-17%) overall.…”

Section: Resultsmentioning

confidence: 99%

Strongyloidiasis screening in migrants living in Spain: systematic review and meta‐analysis

Salvador

Treviño

Bosch-Nicolau

et al. 2019

Objectives To provide information regarding the prevalence of strongyloidiasis among migrants coming from Strongyloides stercoralis‐endemic areas who reside in Spain. Methods Systematic review of the literature and meta‐analysis of studies showing prevalence of S. stercoralis infection among migrants from Latin America, Africa, Eastern Europe, Asia and Oceania who reside in Spain. We included articles published until 30 April 2019 without language restriction. The keywords used for the search included ‘Strongyloides stercoralis’, ‘strongyloidiasis’, ‘Spain’, ‘screening’ and ‘migrants’. Results Twenty‐four studies were included in the review and meta‐analysis, comprising 12 386 screened people. Eleven studies (7020 patients) evaluated the presence of S. stercoralis infection only through investigation of larvae in faeces, showing an overall prevalence of 1% (95%CI 1–1%). Thirteen studies (5366 patients) used a serological test, showing an overall prevalence of 14% (95%CI 11–17%). Strongyloidiasis seroprevalence was 20% (95%CI 15–24%) among migrants from sub‐Saharan Africa, 14% (95%CI 10–18%) among those from Latin America and 8% (95%CI 5–11%) among migrants from North Africa. Conclusions Migrants coming from strongyloidiasis‐endemic areas living in Spain had a high S. stercoralis infection prevalence, particularly those from sub‐Saharan Africa and Latin America. This population should be screened using serology as the most sensitive test for S. stercoralis infection. This could be easily implemented at primary care level.

“…Scarce information about the prevalence of S. stercoralis infection in Bolivia is available, and it comes from studies centred on at‐risk populations . However, studies performed in Bolivian immigrants living in Spain showed a S. stercoralis seroprevalence of 18–44% . Another study performed in Switzerland showed a S. stercoralis seroprevalence of 8.4% among Latin American immigrants (48% from Bolivia) .…”

Section: Discussionmentioning

confidence: 99%

Strongyloides stercoralis infection increases the likelihood to detect Trypanosoma cruzi DNA in peripheral blood in Chagas disease patients

Salvador

Sulleiro

Pirón

et al. 2017