Serological screening and toxoplasmosis exposure factors among pregnant women in the Democratic Republic of Sao Tome and Principe

Hung, Chien‐Ching; Fan, Chia Kwung; Su, Kang‐Yi; Sung, Fung Chang; Chiou, Hung Yi; Gil, Vilfrido; Ferreira, Maria da Conceicao dos Reis; Carvalho, Jose Manuel de; Cruz, Claudina; Lin, Yu Hung; Tseng, Lian Fen; Sao, Ke Yun; Chang, Wen Cheun; Lan, Hung Shue; Chou, Shing Hsien

doi:10.1016/j.trstmh.2006.04.012

Cited by 49 publications

(31 citation statements)

References 20 publications

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“…Water has been implicated as a source of Toxoplasma infection and has been reported globally for pregnant women. 28,30,[37][38][39][40] On the basis of these findings, serial screening for Toxoplasma infection in the first, second, and third trimesters might make it feasible to detect when seroconversion occurs, particularly among high-risk pregnant women.…”

Section: Discussionmentioning

confidence: 99%

Toxoplasmosis-Serological Evidence and Associated Risk Factors among Pregnant Women in Southern Thailand

Nissapatorn

Suwanrath²,

Sawangjaroen³

et al. 2011

The American Society of Tropical Medicine and Hygiene

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Toxoplasma gondii is an important parasite in pregnant women. This case-controlled study assessed the seroprevalence of toxoplasmosis in 640 pregnant women in southern Thailand and identified their associated risk factors. The overall seroprevalence of toxoplasmosis was 181 (28.3%). Of this, 138 (21.6%) were positive for only anti-Toxoplasma immunoglobulin G (IgG) antibody, 43 (6.7%) were positive for both IgG and IgM antibodies, and none were positive for IgM antibody. Multivariate analysis revealed that increasing age (adjusted odds ratio [OR] = 1.64, 95% confidence interval [CI] = 1.01–2.67), living outside Songkhla province (adjusted OR = 1.56, 95% CI = 1.08–2.24), parity (adjusted OR = 1.65, 95% CI = 1.01–2.68), contact with cats (adjusted OR = 1.70, 95% CI = 1.20–2.43), and drinking of unclean water (adjusted OR = 1.70, 95% CI = 1.08–2.68) were factors associated with Toxoplasma seroprevalence. On the basis of the results obtained, a health surveillance program should be initiated as a primary preventive measure for congenital toxoplasmosis and focus on educating women of the child-bearing age group to avoid contact with cats and to strictly practice personal hygiene.

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Section: Discussionmentioning

confidence: 99%

Toxoplasmosis-Serological Evidence and Associated Risk Factors among Pregnant Women in Southern Thailand

Nissapatorn

Suwanrath²,

Sawangjaroen³

et al. 2011

The American Society of Tropical Medicine and Hygiene

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“…In developed countries, the reported seroprevalence was 17.3z in the United Kingdom (9), 31.7z in Upper Austria (10), 43.8z in France (11), 4z in South Korea (12), and 10.3z in Japan (13). In developing countries, 6.1z to 20.0z of pregnant women in Mexico had antiToxoplasma IgG antibodies (14), 49.5z in Brazil (15), 10.6z in Changchun, northern China (16), 28.3z in southern Thailand (17), and 75.2z in Sao Tome and Principe, West Africa (18).…”

Section: Introductionmentioning

confidence: 99%

Seroprevalence, Seroconversion, and Risk Factors for Toxoplasmosis among Pregnant Women in Taipei, Taiwan

Hung

Lee

et al. 2015

Jpn J Infect Dis

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SUMMARY: Herein, we determined the seroprevalence, seroconversion, and risk factors associated with Toxoplasma gondii (T. gondii) infection among pregnant women in Taipei, Taiwan. Pregnant women attending antenatal consultation in a Taipei medical center were invited, and 104 women completed a self-administered structured questionnaire. Venous blood samples were collected during the first and third trimester after consent was obtained. Serum IgG and IgM antibodies (Abs) as well as IgG avidity were analyzed using an enzyme-linked fluorescent assay. Of the samples collected in the first trimester, seven were seropositive for IgG Abs and one was seropositive for IgG ＋ IgM Abs with a borderline avidity index, resulting in an overall seroprevalence of 7.7z. No statistically significant association was found between toxoplasmosis and age, pregnancy history, or any risk factors. Seroconversion was not detected from paired sera between the first and third trimesters. Pregnant women with senior high school education level or those who claimed to knowing Toxoplasma exhibited a significantly higher seroprevalence than those with bachelor degree (P ＝ 0.05) or those who claimed not to have this knowledge (P ＝ 0.05). Therefore, failure to understand the importance of T. gondii infection and the prevention measures resulted in the development of toxoplasmosis among these women.

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“…Most of the studies regarding toxoplasmosis in pregnancy in Brazil [18,19] and other countries [20-28], try to estimate the prevalence of the disease or infection and its determinant factors. As an example, we cite a study with 425 pregnant girls who were receiving prenatal care in basic health care units in the city of Pelotas, Rio Grande do Sul, Brazil which identified that 65% of the pregnant girls did not know about the disease, while most associated it with having cats as pets and less than one third of them associated it with the handling and the consumption of undercooked raw meats and raw vegetables [29].…”

Section: Introductionmentioning

confidence: 99%

Preventive behavior for toxoplasmosis in pregnant adolescents in the state of Ceara, Brazil

et al. 2012

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BackgroundWhen toxoplasmosis is acquired during pregnancy, it can be transmitted to the fetus causing severe lesions in the first two gestational trimesters. This study analyzed the main factors associated with the preventive behavior for toxoplasmosis among pregnant adolescents in the city of Fortaleza in northeast Brazil.MethodsIt is a cross-sectional study conducted from March 2009 to November 2010, with a sample of 320 pregnant adolescents, ages ranging from 12 to 19 years old, receiving prenatal care in the Public Health Care System. Bivariate and multivariate logistic regression model analyses were used to identify the association between preventive behavior for toxoplasmosis, and the independent variables and 95% confidence interval.ResultsWe observed that 16.3% of the pregnant adolescents showed preventive behavior for toxoplasmosis. The factors positively associated to the preventive behavior for toxoplasmosis were: age group between 12 and 14 years old (OR = 2.75; 95%CI 1.23-6.12) and more than two prenatal consultations (OR = 2.19; 95%CI 1.17-4.09).ConclusionsNoteworthy is the importance of a serologic follow-up for pregnant adolescents with clearer and more precise information about risk factors and the importance of adopting preventive behaviors. Thus, it is necessary to establish educational measures for handling food and raising kittens during prenatal care.

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Serological screening and toxoplasmosis exposure factors among pregnant women in the Democratic Republic of Sao Tome and Principe

Cited by 49 publications

References 20 publications

Toxoplasmosis-Serological Evidence and Associated Risk Factors among Pregnant Women in Southern Thailand

Toxoplasmosis-Serological Evidence and Associated Risk Factors among Pregnant Women in Southern Thailand

Seroprevalence, Seroconversion, and Risk Factors for Toxoplasmosis among Pregnant Women in Taipei, Taiwan

Preventive behavior for toxoplasmosis in pregnant adolescents in the state of Ceara, Brazil

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