Serological and molecular studies on<i>Dirofilaria immitis</i>in dogs from Turkey

Şimşek, Sami; Ütük, Armağan Erdem; Köroğlu, Ergün; Rishniw, Mark

doi:10.1017/s0022149x0896079x

Cited by 23 publications

(15 citation statements)

References 15 publications

(21 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This result is close to the previous report by Alves et al (1999) (57.1%). According to some of the researchers, no significant differences have been detected between the sexes (Oge et al, 2003;Song et al, 2003;Simsek et al, 2008). Occult infections may be due to different causes, including treatment with macrocyclic lactones or immune-mediated reactions that are able to eliminate the microfilariae or to decrease the fecundity of adult worms.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Dirofilaria immitis in dogs from Hatay province, Turkey

et al. 2009

View full text Add to dashboard Cite

The present study was conducted to determine the prevalence of canine dirofilariosis in Hatay province, south of Turkey. A total of 269 blood samples were collected from owned dogs in this multi-centre survey between March and July 2006. Blood samples were examined by modified Knott and enzyme-linked immunosorbent assay (ELISA) techniques to detect circulating microfilariae and antigens of Dirofilaria immitis, respectively. Seventy out of 269 dogs (26.0%) were positive for D. immitis. However, 61.4% of positive dogs had occult infection. The prevalence of canine dirofilariosis was heterogeneous in Hatay province, with higher values in shoreline (33.0%) and riverside (30.9%) areas followed by the lowland (25.5%) or mountainous (15.2%) areas. No statistically significant differences were observed in relation to sex (females, 33.3%; males, 24.4%, P>0.05). When evaluating the prevalence of D. immitis by age, the highest prevalence was observed in dogs older than 4 years of age. Large breeds (29.6%) and the dogs living outdoors (30.2%) showed a higher prevalence in comparison to small breeds (21.4%) and the dogs living indoors (10.5%), respectively. In conclusion, according to the results of this study canine dirofilariosis had a high prevalence in Hatay province. Therefore, prophylaxis against heartworm is advisable to decrease the incidence of canine dirofilariosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Prevalence of Dirofilaria immitis in dogs from Hatay province, Turkey

et al. 2009

View full text Add to dashboard Cite

show abstract

“…In Istanbul the infection affects the 1.52% of the dogs (Öncel and Vural, 2005), 2% in the area of Gemlik of Bursa (Civelek et al, 2007), 9.6% in the province of Kayseri (Yildirim et al, 2007), and 26% in the province of Hatay. A study carried out by Simsek et al (2008) reports prevalences of 14.8% in Ankara, 12.3% in Sakarya, 10.5% in Mersin, and 18.3% in Kocaeli. Finally, in the region of Kirikkale positive cases were also reported (58% of the infected dogs were microfilaremic and 27.46% were amicrofilaremic; Yildiz et al, 2008).…”

Section: Epidemiological Situation Of Animal Dirofilariasis In Europementioning

confidence: 97%

Heartworm Disease (Dirofilaria immitis) and Their Vectors in Europe – New Distribution Trends

Morchón¹,

Carretón²,

et al. 2012

View full text Add to dashboard Cite

Cardiopulmonary dirofilariasis is a cosmopolitan disease caused by Dirofilaria immitis, which affects mainly canids and felids. Moreover, it causes zoonotic infections, producing pulmonary dirofilariasis in humans. Heartworm disease is a vector-borne transmitted disease, thus transmission depends on the presence of competent mosquito species, which is directly related to favorable climate conditions for its development and survival. Cardiopulmonary dirofilariasis is mainly located in countries with temperate and tropical climates. Europe is one of the continents where animal dirofilariasis has been studied more extensively. In this article we review the current prevalence of canine and feline cardiopulmonary dirofilariasis in the European continent, the transmission vectors, the current changes in the distribution and the possible causes, though the analysis of the epidemiological studies carried out until 2001 and between 2002 and 2011. The highest prevalences have been observed in the southern European countries, which are considered historically endemic/hyperendemic countries. Studies carried out in the last 10 years suggest an expansion of cardiopulmonary dirofilariasis in dogs toward central and northern Europe. Several factors can exert an influence on the spreading of the disease, such as movement of infected animals, the introduction of new species of mosquitoes able to act as vectors, the climate change caused by the global warming, and development of human activity in new areas. Veterinary controls to prevent the spreading of this disease, programs of control of vectors, and adequate protocols of prevention of dirofilariasis in the susceptible species should be carried out.

show abstract

“…S1 in the supplemental material) (108,123,126,149,312,319,332,349,398,409,410,455,459). Cases of dirofilariasis were first reported in southern Switzerland in 1995 (109).…”

Section: Canine Dirofilariasismentioning

confidence: 99%

Human and Animal Dirofilariasis: the Emergence of a Zoonotic Mosaic

et al. 2012

View full text Add to dashboard Cite

SUMMARY Dirofilariasis represents a zoonotic mosaic, which includes two main filarial species ( Dirofilaria immitis and D. repens ) that have adapted to canine, feline, and human hosts with distinct biological and clinical implications. At the same time, both D. immitis and D. repens are themselves hosts to symbiotic bacteria of the genus Wolbachia , the study of which has resulted in a profound shift in the understanding of filarial biology, the mechanisms of the pathologies that they produce in their hosts, and issues related to dirofilariasis treatment. Moreover, because dirofilariasis is a vector-borne transmitted disease, their distribution and infection rates have undergone significant modifications influenced by global climate change. Despite advances in our knowledge of D. immitis and D. repens and the pathologies that they inflict on different hosts, there are still many unknown aspects of dirofilariasis. This review is focused on human and animal dirofilariasis, including the basic morphology, biology, protein composition, and metabolism of Dirofilaria species; the climate and human behavioral factors that influence distribution dynamics; the disease pathology; the host-parasite relationship; the mechanisms involved in parasite survival; the immune response and pathogenesis; and the clinical management of human and animal infections.

show abstract

Serological and molecular studies onDirofilaria immitisin dogs from Turkey

Cited by 23 publications

References 15 publications

Prevalence of Dirofilaria immitis in dogs from Hatay province, Turkey

Prevalence of Dirofilaria immitis in dogs from Hatay province, Turkey

Heartworm Disease (Dirofilaria immitis) and Their Vectors in Europe – New Distribution Trends

Human and Animal Dirofilariasis: the Emergence of a Zoonotic Mosaic

Contact Info

Product

Resources

About