Serological Analysis of Serum Samples from Humans Exposed to Avian H7 Influenza Viruses in Italy between 1999 and 2003

Puzelli, Simona; Trani, Livia Di; Fabiani, Concetta; Campitelli, Laura; Marco, Maria Alessandra De; Capua, Ilaria; Aguilera, Jean Francois; Zambon, Maria; Donatelli, Isabella

doi:10.1086/444390

Cited by 145 publications

(113 citation statements)

References 11 publications

(13 reference statements)

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“…They have included serosurveys of bird cullers, open bird market workers, swine workers, duck hunters, meat processing workers, veterinarians and poultry workers, concluding that these populations are indeed at greater risk of infection with zoonotic influenza virus 5 , 6 , 8 , 9 , 10 , 11 , 12 , 13 …”

Section: Discussionmentioning

confidence: 99%

Avian influenza and poultry workers, Peru, 2006

Ortiz

Kochel

Capuano

et al. 2007

Influenza Resp Viruses

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Background Currently numerous countries in Asia, Africa and Europe are encountering highly pathogenic avian influenza (AI) infections in poultry and humans. In the Americas, home of the world’s largest poultry exporters, contingency plans are being developed and evaluated in preparation for the arrival of these viral strains. Objectives With this cross‐sectional study, to our knowledge the first in its kind in Central or South America, we sought to learn whether Peruvian poultry workers had evidence of previous AI infection and if so, to determine the risk factors for infection. Methods We performed a cross‐sectional seroprevalence study among 149 workers on a Peruvian poultry farm (132 exposed to poultry and 17 non‐exposed controls), serum samples were tested for human influenza virus exposure using a hemagglutination inhibition (HI) assay. Microneutralization assays were performed on all serum samples to detect antibodies against prototypic AI strains H4 through H12. Results Using multivariate proportional odds modeling we found that the prevalence of elevated titers against AI viruses was low in both groups, exposed and non‐exposed controls. Conclusions No evidence of previous AI infection among Peruvian poultry workers was found in this first cross‐sectional study performed in South America. This first occupational study of AI in Latin America was encouraging, but it likely reflects the sector of poultry production with higher biosecurity.

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Section: Discussionmentioning

confidence: 99%

Avian influenza and poultry workers, Peru, 2006

Ortiz

Kochel

Capuano

et al. 2007

Influenza Resp Viruses

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“…However, HPAI viruses may emerge by mutation from low pathogenicity AI (LPAI) viruses of the H5 and H7 subtypes circulating in domestic poultry [2,3], and both LPAI and HPAI viruses can infect humans [4][5][6], which stresses the need for the monitoring and control of LPAI viruses in poultry.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of interventions and vaccination strategies for low pathogenicity avian influenza: spatial and space–time analyses and quantification of the spread of infection

et al. 2009

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“…26,27 However, several studies indicate that workers have been infected during AI outbreaks in poultry. [27][28][29][30][31][32][33] A serological evaluation of workers exposed during the HPAI H5N1 outbreak in Hong Kong in 1997 found that approximately 3% of government workers involved in the poultry culling operation and 10% of poultry workers were seropositive. 28 During a 2003 outbreak of HPAI H7N7 in the Netherlands, infection was confirmed in 89 people, with conjunctivitis being the predominant symptom reported.…”

Section: Discussionmentioning

confidence: 99%

Protecting Poultry Workers from Exposure to Avian Influenza Viruses

et al. 2008

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Emerging zoonotic diseases are of increasing regional and global importance. Preventing occupational exposure to zoonotic diseases protects workers as well as their families, communities, and the public health. Workers can be protected from zoonotic diseases most effectively by preventing and controlling diseases in animals, reducing workplace exposures, and educating workers. Certain avian influenza viruses are potential zoonotic disease agents that may be transmitted from infected birds to humans. Poultry workers are at risk of becoming infected with these viruses if they are exposed to infected birds or virus-contaminated materials or environments. Critical components of worker protection include educating employers and training poultry workers about occupational exposure to avian influenza viruses. Other recommendations for protecting poultry workers include the use of good hygiene and work practices, personal protective clothing and equipment, vaccination for seasonal influenza viruses, antiviral medication, and medical surveillance. Current recommendations for protecting poultry workers from exposure to avian influenza viruses are summarized in this article.

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Serological Analysis of Serum Samples from Humans Exposed to Avian H7 Influenza Viruses in Italy between 1999 and 2003

Cited by 145 publications

References 11 publications

Avian influenza and poultry workers, Peru, 2006

Avian influenza and poultry workers, Peru, 2006

Evaluation of interventions and vaccination strategies for low pathogenicity avian influenza: spatial and space–time analyses and quantification of the spread of infection

Protecting Poultry Workers from Exposure to Avian Influenza Viruses

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