Serological analysis of autoantibody mimicking anti-Rh(e) specificity: a case report

Abstract

Mimicking antibodies are described as autoantibodies with the “wrong” specificity, possessing both specificity and panreactivity. We report the case of a female patient with suspected hemolytic anemia in whom an autoantibody mimicking anti-Rh(e) specificity was found in both plasma and red blood cell samples. Mimicking antibodies are not usually identified in the clinic; however, it is still necessary to determine the specificity of mimicking antibodies to avoid antigen-positive blood transfusions and achieve maximum transfusion compatibility.