2023
DOI: 10.3201/eid2902.221458
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Serologic Evidence of Orientia Infection among Rural Population, Cauca Department, Colombia

Abstract: We assessed serum samples collected in Cauca Department, Colombia, from 486 persons for Orientia seroreactivity. Overall, 13.8% showed reactive IgG by indirect immunofluorescence antibody assay and ELISA. Of those samples, 30% (20/67) were confirmed to be positive by Western blot, showing > 1 reactive band to Orientia 56-kD or 47-kD antigens.

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“…In Colombia, no attempt to detect the bacterium or the exposition to it was made until 2022, when a study found seropositivity to Orientia spp., confirmed with Western blot, among inhabitants of four municipalities of Cauca department ( Table 2 ) ( Figure 1 J) [ 99 ], which should encourage to perform more studies to establish if Orientia is part of febrile illnesses in the region, and if so, determine which species are involved, as well as its possible implications for Colombian public health or whether further surveillance by local health systems is warranted.…”
Section: Orientiamentioning
confidence: 99%
“…In Colombia, no attempt to detect the bacterium or the exposition to it was made until 2022, when a study found seropositivity to Orientia spp., confirmed with Western blot, among inhabitants of four municipalities of Cauca department ( Table 2 ) ( Figure 1 J) [ 99 ], which should encourage to perform more studies to establish if Orientia is part of febrile illnesses in the region, and if so, determine which species are involved, as well as its possible implications for Colombian public health or whether further surveillance by local health systems is warranted.…”
Section: Orientiamentioning
confidence: 99%