“…Bluetongue is an important and abortive infection of both domestic (Sheep, goat, camels, etc) and wild ruminants which clinical characterized by different symptoms such as congestion, cyanosis of the tongue, hemorrhage near the base of the pulmonary artery, oedema, reduced wool quality, poor subsequent reproductive performance, decrease milk production (Verwoerd and Erasmus 2004, Aradaib et al 2005, Gür 2008, Maclachlan et al 2008. BTV infection is a seasonal infection (Carpenter et al 2013) and may cause economic losses (van der Sluijs et al 2012) in flocks and transmitted by Culicoides species; therefore, the prevalence of the BTV infection increases during the spring, summer, and fall when the density of Culicoides increases (Tabachnick 1996, Meiswinkel et al 2008, Darpel et al 2011, van der Sluijs et al 2012.…”