Seroepidemiology of whooping cough in the Czech Republic: estimates of incidence of infection in adults

Chlíbek, Roman; Smetana, Jan; Sosovickova, Renata; Fabiánová, Kateřina; Zavadilová, Jana; Dítě, Petr; Gal, Peter; Naplava, P; Lžičařová, D

doi:10.1016/j.puhe.2017.05.012

Cited by 10 publications

(6 citation statements)

References 23 publications

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“…So a decrease in the immunity level can lead to an increased incidence of pertussis at older ages (27). This finding confirmed by other studies (28,29).…”

Section: Discussionsupporting

confidence: 82%

Spatio-temporal analysis of Pertussis using geographic information system among Iranian population during 2012-2018

Alimohamadi

Zahraei

Karami

et al. 2020

mjiri

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“…So a decrease in the immunity level can lead to an increased incidence of pertussis at older ages (27). This finding confirmed by other studies (28,29).…”

Section: Discussionsupporting

confidence: 82%

Spatio-temporal analysis of Pertussis using geographic information system among Iranian population during 2012-2018

Alimohamadi

Zahraei

Karami

et al. 2020

mjiri

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“…The morbidity due to pertussis steeply 44 declined after the compulsory vaccination was introduced in 1958 (Vysoka- Burianova et al, 1976). As 45 in other countries with high vaccination coverage, the incidence of pertussis in the Czechoslovakia 46 and later on in the Czech Republic started to rise progressively since the 1990s (Raguckas et al, 2007, Fabianova et al, 2010, Sealey et al, 2016 and this trend accelerated strongly upon switch to 48 acellular pertussis subunit vaccine use in 2007 (Chlibek et al, 2017). 49…”

mentioning

confidence: 89%

Comparative genomics of Czech vaccine strains of Bordetella pertussis

Dienstbier

Pouchnik

Wildung

et al. 2018

Pathogens and Disease

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Bordetella pertussis is a strictly human pathogen causing the respiratory infectious disease called whooping cough or pertussis. B. pertussis adaptation to acellular pertussis vaccine pressure has been repeatedly highlighted, but recent data indicate that adaptation of circulating strains started already in the era of the whole cell pertussis vaccine (wP) use. We sequenced the genomes of five B. pertussis wP vaccine strains isolated in the former Czechoslovakia in the pre-wP (1954-1957) and early wP (1958-1965) eras, when only limited population travel into and out of the country was possible. Four isolates exhibit a similar genome organization and form a distinct phylogenetic cluster with a geographic signature. The fifth strain is rather distinct, both in genome organization and SNP-based phylogeny. Surprisingly, despite isolation of this strain before 1966, its closest sequenced relative appears to be a recent isolate from the US. On the genome content level, the five vaccine strains contained both new and already described regions of difference. One of the new regions contains duplicated genes potentially associated with transport across the membrane. The prevalence of this region in recent isolates indicates that its spread might be associated with selective advantage leading to increased strain fitness.

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“…Pertussis incidence figures are strongly heterogeneous across different countries [5][6][7][8] and are often not consistent with seroepidemiological studies, which have hypothesised that the true incidence of the disease might be much higher than reported by surveillance systems [9,10].…”

Section: Introductionmentioning

confidence: 99%

The impact of pertussis in infants: insights from a hospital-based enhanced surveillance system, Lazio region, Italy, 2016 to 2019

et al. 2021

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Background Routine surveillance systems for pertussis often suffer from under-recognition and under-reporting. Aim Our aim was to describe the epidemiology and the clinical features of pertussis in children younger than 1 year in an Italian region, detected through an enhanced hospital surveillance system. Methods From 2016 to 2019, we monitored the incidence and the clinical characteristics of hospitalised pertussis cases younger than 1 year in two paediatric hospitals involved in the PERTINENT project. Results We detected 141 pertussis cases, corresponding to an estimated incidence of 105.8 per 100.000 in 2016, 91.7 per 100.000 in 2017, 64.5 per 100.000 in 2018 and 40.9 per 100.000 in 2019, based on the hospitals’ catchment area, roughly corresponding to the Lazio region. A total of 101 cases (77.1%) had a household member with cough or other respiratory symptoms. The most frequent combination of symptoms was paroxysmal cough with apnoea in the absence of fever. Almost 40% had been prescribed an antibiotic treatment before hospitalisation, and the median time from symptom onset to contact with the hospital was 8 days. Thirty-one (22.0%) had complications. Conclusion An enhanced surveillance system showed a high incidence of pertussis among infants in the Lazio region, where the impact of this disease may still be underestimated. Increasing the coverage of pertussis immunisation among pregnant women and improving the capacity for early detection in primary care may contribute to reducing the impact of pertussis among infants.

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Seroepidemiology of whooping cough in the Czech Republic: estimates of incidence of infection in adults

Cited by 10 publications

References 23 publications

Spatio-temporal analysis of Pertussis using geographic information system among Iranian population during 2012-2018

Spatio-temporal analysis of Pertussis using geographic information system among Iranian population during 2012-2018

Comparative genomics of Czech vaccine strains of Bordetella pertussis

The impact of pertussis in infants: insights from a hospital-based enhanced surveillance system, Lazio region, Italy, 2016 to 2019

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