Seroepidemiology of <i>Toxoplasma gondii</i> Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City

Alvarado‐Esquivel, Cosme; Corella-Madueno, Maria Alba Guadalupe; Hernández‐Tinoco, Jesús; Rascón-Careaga, Antonio; Sánchez‐Anguiano, Luis Francisco; Martínez‐Robinson, Karla G.; Aldana-Madrid, María Lourdes; Quizan-Plata, Trinidad; Cáñez-Carrasco, María Guadalupe

doi:10.14740/jocmr3284w

Cited by 6 publications

(5 citation statements)

References 25 publications

(33 reference statements)

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“…The seroprevalence found in the present study is similar to T. gondii seroprevalences reported in pregnant women in other northern Mexican cities including Durango (6.1%), 10 and Aguascalientes (6.2%) 13 and women at reproductive age in the northwestern Mexican city of Hermosillo, Sonora (3.6%). 12 On the other hand, the seroprevalence of T. gondii infection found in the present study is lower than the 8.2% seroprevalence of this infection found in pregnant women in rural Durango State. 11 These studies used the same immunoassay to detect anti-T. gondii IgG antibodies.…”

Section: Discussioncontrasting

confidence: 83%

“…9 Whereas seroprevalences of 6.1% and 8.2% were found in pregnant women in the northern Mexican city of Durango, 10 and rural Durango, 11 respectively. Seroprevalences of 3.6% and 6.2% were found in women of reproductive age in the northwestern Mexican city of Hermosillo, 12 and in pregnant women in the central Mexican city of Aguascalientes, 13 respectively. A summary of epidemiological data of previous studies of T. gondii infection in pregnant women in Mexico is shown in table 1.…”

Section: Strengths and Limitations Of This Studymentioning

confidence: 95%

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Toxoplasma gondiiinfection in pregnant women: a cross-sectional study in Matehuala City, Mexico

et al. 2020

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ObjectivesThis study aimed to determine the seroprevalence of Toxoplasma gondii (T. gondii) infection in pregnant women in Matehuala City, Mexico; and the associated risk factors.DesignA cross-sectional study.SettingMatehuala City, Mexico.Participants311 pregnant women.Primary and secondary outcome measuresSera of women were analysed for anti-T. gondii IgG and IgM antibodies by commercially available immunoassays. Bivariate and multivariate analyses were used to assess the association between T. gondii seroprevalence and the characteristics of the pregnant women.ResultsThirteen (4.2%) of the 311 pregnant women studied were positive for anti-T. gondii IgG antibodies. No anti-T. gondii IgM antibodies were found in anti-T. gondii IgG seropositive women. No association between seropositivity and history of blood transfusion, transplantation, caesarean sections, deliveries, miscarriages or number of pregnancies was found. Logistic regression analysis of sociodemographic, behavioural and housing variables showed that availability of potable water at street represented a risk factor for T. gondii infection (age-adjusted OR=2.18; 95% CI: 1.05 to 4.53; p=0.03), whereas being born in Mexico was a protective factor for infection (age-adjusted OR=0.01; 95% CI: 0.001 to 0.35; p=0.008).ConclusionsIn this first study on the seroepidemiology of T. gondii infection in pregnant women in Matehuala, we conclude that the seroprevalence of T. gondii infection is low and similar to those reported in pregnant women in other Mexican cities. However, the seroprevalence found is lower than those reported in pregnant women in other countries in the Americas and Europe. Two risk factors associated with T. gondii infection were identified. Results of the present study may help for the optimal planning of preventive measures against toxoplasmosis in pregnant women.

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Section: Discussioncontrasting

confidence: 83%

Section: Strengths and Limitations Of This Studymentioning

confidence: 95%

Toxoplasma gondiiinfection in pregnant women: a cross-sectional study in Matehuala City, Mexico

et al. 2020

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“…Alvarado-Esquivel et al reported a similar finding. 29 These exposures to T. gondii could possibly be because of other risk factors like working with raw meat, which were not assessed in our study.…”

Section: Factors Associated With Seropositivitymentioning

confidence: 86%

“…23 The seroprevalence is the same as in Mexico, which has a similar arid climate. 29 A review of studies conducted in Africa found a median seroprevalence of T. gondii of 37%, with rates ranging from 6.4% to 74.5%. 12 Very little is known about the burden of CT in developing countries.…”

Section: Seroprevalence Of Anti-toxoplasma Gondii Iggmentioning

confidence: 99%

Seroprevalence of Toxoplasma gondii infection among pregnant women in Windhoek, Namibia, in 2016

Colf

Zyl

Noden

et al. 2020

Southern African Journal of Infectious Diseases

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Background: When a pregnant woman contracts Toxoplasma gondii (T. gondii) infection during pregnancy, it may be vertically transmitted to the foetus. Information on the incidence of congenital toxoplasmosis (CT) in developing countries is scarce. Most studies focus on the seroprevalence of T. gondii infection among pregnant women. This study aimed to determine the seroprevalence of T. gondii infection among pregnant women attending public antenatal care in Windhoek, Namibia, in 2016.Methods: In this descriptive study, 344 urban pregnant women attending public antenatal care were voluntarily enrolled in the study. Seroprevalence of anti-T. gondii Immunoglobulin G (IgG) was determined by automated immunoassay. Samples with a positive T. gondii IgG result were tested for T. gondii Immunoglobulin M (IgM) and specific IgG avidity by using an enzyme-linked immunosorbent assay (ELISA) test. A questionnaire captured demographic data and exposure to risk factors. Data were analysed using Statistical Package for the Social Sciences (SPSS) and R.Results: Anti-T. gondii IgG was found in nine (2.61%) pregnant women. There was no association of anti-T. gondii IgG with demographic characteristics or exposure to risk factors.Anti-T. gondii IgM was positive in one (0.3%) woman, while three (0.9%) women had borderline anti-T. gondii IgM results. Specific IgG avidity was low, equivocal and high in 0%, 33% and 67% of seropositive pregnant women, respectively.Conclusion: Seroprevalence of anti-T. gondii IgG is much lower in Namibia than is reported in other developing countries. Investigation into specific IgM seropositivity and IgG avidity showed that pregnant women in the central region of Namibia are at low risk of vertical transmission and development of CT.

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“…All the researches were narrowed into specified status like pregnancy and gyneco-obstetric problems. None of these fully included all categories of women of the childbearing age range (Rahman, et al [19][20][21][22][23][24][25][26][27][28][29][30][31]).…”

Section: Discussionmentioning

confidence: 99%

"Review On: Seroprevalence of Toxoplasma gondii Infection in Women of Child-Bearing Age"

Khanum

2023

BJSTR

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Toxoplasmosis is a zoonotic disease transmitted by the protozoan parasite Toxoplasma gondii. The disease is common worldwide due to its ability to infect a wide range of warm-blooded animals including humans. Areas with poor hygiene and infrastructure along with climatic conditions where the parasites tend to exist and most importantly unawareness of the presence of asymptomatic condition has caused a persistent prevalence of infection in women of childbearing age. This persistency later becomes the principal cause for congenital toxoplasmosis. Since more than 80% of immunocompetent individuals remain asymptomatic or exhibit only flu-like symptoms, a measure of seroprevalence can help to find any exposure to infection by identifying specific IgG and IgM antibodies. So, this review has been summarized to assess the prevailing seropositivity of T. gondii infection among women who are going through childbearing age of 15-49 years and the possible associated factors behind this prevalence rate.

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Seroepidemiology of Toxoplasma gondii Infection in Women of Reproductive Age: A Cross-Sectional Study in a Northwestern Mexican City

Cited by 6 publications

References 25 publications

Toxoplasma gondiiinfection in pregnant women: a cross-sectional study in Matehuala City, Mexico

Toxoplasma gondiiinfection in pregnant women: a cross-sectional study in Matehuala City, Mexico

Seroprevalence of Toxoplasma gondii infection among pregnant women in Windhoek, Namibia, in 2016

"Review On: Seroprevalence of Toxoplasma gondii Infection in Women of Child-Bearing Age"

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