Seroepidemiologic Study of Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus and Syphilis Infections in Iranian Blood Donors

Khedmat, Hossein; Fallahian, Farahnaz; Abolghasemi, Hassan; Alavian, Seyed Moayed; Hajibeigi, Bashir; Miri, Seyyed Mohammad; Jafari, Amir Masoud

doi:10.3923/pjbs.2007.4461.4466

Cited by 24 publications

(5 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…13-16-18 While in Lahore, the second largest city of Pakistan with a population of more than 7 million peoples 25 , HCV prevalence was estimated from 0.58-17.78%. 15,18,24,[26][27][28][29] Our study results are in agreement to all these study. Another similar works conducted in other province of Pakistan also to collect the data about the incident rate in their regions.…”

Section: Methodssupporting

confidence: 91%

“…For example, higher HCV prevalence have been reported in India (1.5%), Malaysia (2.3%), Philippines (2.3%), Africa (6.5%), and Egypt (20%). 29,30 But in recent studies from Iran, Kashmir, India, turkey, Nigeria, Bangladesh, brazil) also reported very low rate of HCV positivity in asymptomatic blood donors community as compare to present study from Pakistan. 28,[31][32][33][34][35][36].…”

Section: Methodscontrasting

confidence: 53%

See 1 more Smart Citation

Hepatitis C Virus Infection

Saeed¹,

Iram²,

Hussain³

et al. 2016

TPMJ

View full text Add to dashboard Cite

Hepatitis C virus (HCV) is the main causative agent of post transfusion hepatitis.The virus is distributed worldwide with varying prevalence in different countries, which couldeasily lead to chronic infections, cirrhosis, and even hepatocellular carcinoma (HCC). The aimof this study was to determine the prevalence of HCV infection among asymptomatic Pakistaniblood donors community. Study Design: Cross sectional study. Setting: Medicine Department,Allama Iqbal Medical College (AIMC) & Jinnah Hospital Lahore (JHL). Period: One year (Jan2014 to 30 Dec 2014). Material & Methods: A total of 18,274 blood samples were collected fromasymptomatic healthy blood donors (age range 19–59 years) at allama iqbal Medical College& Jinnah Hospital Lahore Pakistan. Blood samples were screened for anti-HCV by Immunochromatographictechnique (ICT). Results: Out of 18,274 blood samples, the overall HCVprevalence was 2.62%. Among the HCV positive cases, male were more prevalent, accordingto marital status married individuals were more prevalent and the age group with 31-40 yearswas more frequently infected.in relation with blood group high frequency of HCV positivityseen in Blood Group B. Conclusion: We conclude that HCV is asymptomatic infection andeasily can lead to chronic stat. therefore control of transmission requires continuous monitoringand surveillance. Trend of HCV infection is decreasing in recent years, In comparison withcountries in geographic region, Pakistan has still high rate of HCV infection. The HCV epidemicin Pakistan continues due to lack of education and awareness of the disease. A multidisciplinaryapproach and the best policies for management will be required to adopt suitable technicalmethods increase awareness in both lay and medical communities. And produce more accuratediagnosis and effective treatment of HCV patients

show abstract

Section: Methodssupporting

confidence: 91%

Section: Methodscontrasting

confidence: 53%

Hepatitis C Virus Infection

Saeed¹,

Iram²,

Hussain³

et al. 2016

TPMJ

View full text Add to dashboard Cite

show abstract

“…Compared to the results obtained in other studies, Yildiz et al reported that 0.10% of blood donors in Adana, Turkey were positive (4). Additionally, syphilis positivity was reported as only 0.004% and 0.01% in Iran (15,16).…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Transfusion Transmissible Infections Among Blood Donors in South Khorasan Province, Iran: An 11-Year Study

Mesbahzadeh

Ameli²,

Moghadam

et al. 2021

Mod Care J

View full text Add to dashboard Cite

Background: Transfusion transmissible infections (TTIs) are the most frequent complication of blood transfusions. This fact stresses the need for regular evaluation and monitoring of TTIs in blood donors. Objectives: This study was done to determine the prevalence of the hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and syphilis among blood donors at the South Khorasan Transfusion Center (SKBTC) in South Khorasan Province, Iran. This report is the first of its kind that has been performed in this region. Methods: A retrospective study was carried out on 165,267 blood donors at the SKBTC from 2006 to 2016. Data were analyzed on the metrics of donation status, age, gender, educational level, and serologic results for the infectious markers. Statistical analysis was performed using SPSS software (version 16.0). Results: The overall seroprevalence rates of HBV, HCV, and HIV infections per 100,000 donations were 247, 21, and 0.6, respectively. There was no positive donor for syphilis. HBV and HCV infections in first-time donors were present at significantly higher rates than in regular and repeat donors (P < 0.001 and P = 0.003, respectively). Although gender was not found to be significantly associated with HBV and HCV (P = 0.32), there was a significant relationship between younger age (P < 0.001) as well as lower educational level and hepatitis agents (P < 0.001). Moreover, being single evinced a significant association with HCV seropositivity (P = 0.001). Conclusions: This report found a decreased prevalence of TTIs relative to the most of previous reports. This decrease may have resulted from public health programs, improved donor selection, improved recruitment of repeat/regular donors, and the use of highly sensitive kits for the screening procedure.

show abstract

“…A description of the key characteristics of the included studies is provided in Table 1. The 15 studies included 1,022,254 participants, with sample sizes ranging from 41 (14) to 345,412 (7) with a median sample size of 635. All included studies were cross-sectional and most (n=13) had recruited through a convenience sampling approach; only two studies used probabilistic sampling methods.…”

Section: Participants and Study Characteristicsmentioning

confidence: 99%

“…In Iran, the prevalence of syphilis was 4.66% among patients referred to a medical clinic with clinical symptoms (6). Another study carried out on blood donors in Iran, indicated that the prevalence of syphilis was approximately 0.004% (7) (7). Although the prevalence of syphilis is low in both men and women, the disease is still common among high-risk groups in the country, including female sex workers (8,9).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Syphilis Infections among the Iranian Population: A Systematic Review and Meta-Analysis

Esmaeilzadeh¹,

Mohammadi²,

Amjadipour³

et al. 2022

ijph

View full text Add to dashboard Cite

Background: Syphilis is one of the most important sexually transmitted infections (STI) and a public health problem, but the literature describing the true burden of syphilis is limited. In Iran, there are no accurate results on the prevalence of syphilis. This study aimed to conduct a systematic review and meta-analysis of syphilis in Iran. Methods: Following PRISMA guidelines, we conducted a systematic review and meta-analysis of studies published on the prevalence of Syphilis in Iran. We systematically reviewed the literature to identify eligible studies as of Sep 13, 2020, in international and national databases. The results are presented in the form of forest plots and tables. Pooled prevalence and 95% confidence intervals were calculated using Der Simonian and Laird method. Perform subgroup analysis through population, gender, city, and diagnostic tests to assess the source of heterogeneity. Results: We reviewed 1,229 papers and reports, and extracted data from 15 eligible records. The prevalence of combined syphilis in Iran is 0.1% (95% confidence interval [95% CI] 0.1-0.1%). The prevalence of syphilis was 0.4% in men (95% confidence interval [95% CI] -0.3, 1%) and 0.6% in women (95% confidence interval [95% CI] (0.1, 1%)). The cumulative meta-analysis showed a decline in the prevalence of syphilis between the years 1999 and 2015. Conclusion: The prevalence of syphilis in Iran is low. In the past few decades, the prevalence of syphilis across the country has declined. Syphilis infection is a small burden that needs to be revised in the implementation of high-cost screening programs.

show abstract

Seroepidemiologic Study of Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus and Syphilis Infections in Iranian Blood Donors

Cited by 24 publications

References 23 publications

Hepatitis C Virus Infection

Hepatitis C Virus Infection

Prevalence of Transfusion Transmissible Infections Among Blood Donors in South Khorasan Province, Iran: An 11-Year Study

Prevalence of Syphilis Infections among the Iranian Population: A Systematic Review and Meta-Analysis

Contact Info

Product

Resources

About