Serodiagnosis of Lyme Borreliosis

Wilske, Bettina

doi:10.1002/9780470933961.ch10

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2017

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Cited by 3 publications

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“…Lyme is a multisystemic infectious disease caused by spirochetes of the Borrelia burgdorferi sensu lato genogroup, found in Europe, North America and northern Asia 1. The regional disparities are due to differences in prevalence of the arthropod vector and reservoir animals 2.…”

Section: Introductionmentioning

confidence: 99%

Diagnosis of Lyme-associated uveitis: value of serological testing in a tertiary centre

et al. 2017

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Section: Introductionmentioning

confidence: 99%

Diagnosis of Lyme-associated uveitis: value of serological testing in a tertiary centre

et al. 2017

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Neurologische Manifestationen der Lyme-Borreliose

Kristoferitsch

1991

Infection

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After the isolation of Borrelia burgdorferi, the previously unknown causative agent of Lyme disease, two neurological disorders, Bannwarth's syndrome and acrodermatitis chronica atrophicans-associated neuropathy, which have been known in Europe for decades, gained new interest. With the availability of serodiagnostic tests, a chronic debilitating disorder--progressive borrelia encephalomyelitis--was found to be caused by chronic infection with B. burgdorferi. Beside these typical manifestations, a growing number of publications about various neurological phenomena appeared, which were thought to be caused by B. burgdorferi. This assumption was based in many cases on the results of serodiagnostic tests only. Considerations for causal connections were frequently lacking. While prior to the availability of serodiagnostic tests neurological manifestations of Lyme borreliosis frequently remained undiagnosed, we now face a tendency for overdiagnosis. The great variety of neurological manifestations in Lyme borreliosis--most of them can also be attributed to other conditions--and the high rate of seropositivity for B. burgdorferi amongst the population living in endemic areas require strict criteria for the correct diagnosis of new and typical neurological manifestations.

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