Serodiagnosis of<i>Helicobacter pylori</i>Infection in Korean Patients Using Enzyme-Linked Immunosorbent Assay

Kim, S Y; Ahn, Jong-Mo; Ha, Young Ju; Doh, Hyounmie; Jang, Myoung Ho; Chung, Soo Il; Park, H J

doi:10.1080/01971529808005485

Cited by 43 publications

(36 citation statements)

References 16 publications

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“…The kit in this study used H. pylori antigen obtained from Korean H. pylori strains, and in Korean adults had a sensitivity and specificity of 97.8% and 92.0%, respectively. 17 …”

Section: H Pylori Serologic Analysismentioning

confidence: 99%

The effects of Helicobacter pylori infection on intraocular pressure in anterior uveitis

Kim

Park

Choi

et al. 2012

Eye

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“…The kit in this study used H. pylori antigen obtained from Korean H. pylori strains, and in Korean adults had a sensitivity and specificity of 97.8% and 92.0%, respectively. 17 …”

Section: H Pylori Serologic Analysismentioning

confidence: 99%

The effects of Helicobacter pylori infection on intraocular pressure in anterior uveitis

Kim

Park

Choi

et al. 2012

Eye

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“…It has been suggested that enzyme immunoassay (EIA) kits validated in one region may yield variable diagnostic performances in other regions (18,19,22,25,33). The antigenic heterogeneity of Helicobacter pylori and geographic variations in the immune response to H. pylori antigens have been suggested to be possible contributing factors.…”

mentioning

confidence: 99%

Evaluation of the Effects of Strain-Specific Antigen Variation on the Accuracy of Serologic Diagnosis of Helicobacter pylori Infection

Marchildon¹,

Sugiyama

Fukada

et al. 2003

J Clin Microbiol

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It has been suggested that enzyme immunoassay (EIA) kits validated in one region may yield variable diagnostic performance results in different regions, possibly due to strain-specific differences in antibody responses in different populations. We tested 13 C-urea breath test-characterized serum samples from 109 U.S. patients and 288 Japanese patients using enzyme immunoassay with different preparations of high-molecularweight cell-associated (HM-CAP) antigens that are conserved across Helicobacter pylori strains. Replicate antigens were prepared from five H. pylori clinical isolates. Eight antigen preparations were evaluated: two of U.S. origin and six of Japanese origin. The accuracies achieved with the eight antigen preparations ranged from 94.4 to 96.3% with the U.S. samples. With the Japanese samples the accuracies achieved ranged from 92.3 to 97.2%. Use of a pool of HM-CAP antigens prepared from isolates from Japan resulted in a higher median enzyme immunoassay value and slightly fewer samples with indeterminate results compared to the results obtained by use of the U.S. standard HM-CAP antigen for H. pylori-positive patients (accuracies, 97.2 and 92.3%, respectively), suggesting that variations in performance between both antigen source and patient population might be reduced by using antigens pooled from several strains.

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“…[6][7][8] There are various diagnostic methods for H. pylori infection including invasive tests and non-invaisive tests. Invasive test are endoscopy, culture, molecular methods, 11 These sensitivity and specificity are not worse, but even better than those of other recent non-invasive methods. 10 A limitation of this method is that it does not discriminate between current and old infection as it is a serology test.…”

Section: Discussionmentioning

confidence: 99%

Association between Helicobacter pylori infection and Posner–Schlossman syndrome

Choi

Kim

et al. 2009

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Objective: To investigate possible association between Helicobacter pylori infection and Posner-Schlossman syndrome. Methods: In a prospective study, 40 subjects with Posner-Schlossman syndrome were examined. As a control group, 73 subjects without Posner-Schlossman syndrome were selected for comparison with the study group. All participants underwent serologic analysis for the presence of H. pylori infection by an enzyme-linked immunosorbent assay. Positive rate of serum anti-H. pylori IgG was compared between Posner-Schlossman syndrome patients and control participants. Results: The rate of positive titre (415 U/ml) of H. pylori was 80.0% in the Posner-Schlossman syndrome group and 56.2% in control group, showing significant difference (Fischer's exact, P ¼ 0.014). Multivariate analysis adjusted for various systemic factors revealed that positive titre of anti-H. pylori IgG was a significant risk factor for Posner-Schlossman syndrome with an odds ratio, (4.84, 95.0% CI: 1.10-21.24, P ¼ 0.037). Conclusions: H. pylori infection occurred significantly more often in PosnerSchlossman syndrome patients. This study suggests that exposure to H. pylori infection is associated with Posner-Schlossman syndrome in Korea.

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Serodiagnosis ofHelicobacter pyloriInfection in Korean Patients Using Enzyme-Linked Immunosorbent Assay

Cited by 43 publications

References 16 publications

The effects of Helicobacter pylori infection on intraocular pressure in anterior uveitis

The effects of Helicobacter pylori infection on intraocular pressure in anterior uveitis

Evaluation of the Effects of Strain-Specific Antigen Variation on the Accuracy of Serologic Diagnosis of Helicobacter pylori Infection

Association between Helicobacter pylori infection and Posner–Schlossman syndrome

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