2020
DOI: 10.21203/rs.3.rs-97191/v1
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Seroconversion for SARS-CoV-2 in rheumatic patients on synthetic and biologics Disease Modifying Anti-Rheumatic Drugs in São Paulo, Brazil

Abstract: Introduction - To date, there is a lack of information on how immunomodulatory drugs for autoimmune rheumatic diseases (ARD) impair humoral immune response following SARS-CoV-2 exposure. Hence, we examined anti-SARS-CoV-2 IgG/IgM positivity in ARD patients on Disease Modifying Anti-Rheumatic Drugs (DMARDs).Methods - We conducted a prospective study with ARD patients on different synthetic or biologic DMARDs (sDMARDs or bDMARDs) and control patients without DMARDs. All patients underwent a clinical baseline int… Show more

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