Sero-Prevalence of HBs Ag, HCV and HIV among Blood Donors in Three Blood Bank Centers in Sana'a city: Yemen

Alzubiery, Tawfique KA; Alharazi, Talal; Alsumairy, Hafez; Al-Zubiery, Adel

doi:10.14302/issn.2576-6694.jbbs-17-1853

Cited by 4 publications

(5 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is consistent with the study carried out in Basra, Iraq (2.3%), and Sana’a, Yemen (2.7%). 16 Statistically, no difference exists between HBsAg rates in males and females ( P = 0.808). Similarly, the prevalence was reported with the same findings ( P = 0.464) with rates of 2.4% and 1.7% in males and females, 45 respectively.…”

Section: Discussionmentioning

confidence: 91%

“… 19 However, the seropositivity rate of the present study was higher than our previous study (1.9%). 16 A low prevalence of HBsAg was reported in Iraq (0.24%), 20 Jordan (0.3%), 21 and Malaysia (0.03%). 22 The present study revealed a lower prevalence rate of HBsAg than those reported rates in Saudi Arabia (3.24%), 23 Yemen (4.1%), 14 Sudan (5.8%), 24 Nigeria (5.8%), 25 Ethiopia (3.0%), 26 Cameroon (11.2%), 27 the Central African Republic (16.7%) 28 and Mauritania (11.8%).…”

Section: Discussionmentioning

confidence: 95%

“… 39 This explained the difference in the prevalence rates of HBsAg (2.0% and 3.1%) and Anti-HBcAb (10.3% and 11.5%) by ECL and EIA in this present study and the previous study, where the rate of HBs was 4.1% and 1.9% by ECL and EIA, respectively. 14 , 16 …”

Section: Discussionmentioning

confidence: 99%

“… 14 , 35 , 49 A recent study revealed prevalence rates of HBsAg and Anti-HBc Ab among the different age groups fairly similar to that study conducted in Sana’a city, Yemen. 16 …”

Section: Discussionmentioning

confidence: 99%

“…Previous studies revealed different results regarding viral hepatitis and HIV prevalence among blood donors. 14 , 16 It was noted that there was a discrepancy in the results, necessitating more investigation to improve and understand these variations and their impact. Hence, the purpose of this study was to update the prevalence rate of HBsAg and anti-HBc among blood donors and determine the reliability of using chemiluminescence and ELISA techniques as well as identifying the effect of duplicated or repeated blood donations on the results.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Updated Seroprevalence of Hepatitis B Surface Antigen and Anti-Hepatitis Core Antibody Among Blood Donors in Yemen

Alzubiery¹,

Alharazi²,

Alcantara³

et al. 2022

IDR

View full text Add to dashboard Cite

Purpose Hepatitis B virus (HBV) is one of the most common infectious pathogens worldwide. Various studies found a prevalence of HBV infection among blood donors ranging from 2% to 18%. Hence, this study aimed to provide an updated prevalence of HBsAg and anti-HBcAb among blood donors. Patients and Methods This was a cross-sectional study to investigate the donation records of blood donors in Sana’a, Yemen, over one year (January to December 2019). Eligible blood donors were included in the study. The serum samples of blood donors were tested for HBsAg and anti-HBcAb (IgG & IgM) using the electrochemiluminescence (ECL) and enzyme immunoassay (EIA) techniques. Results A total of 16,367 blood donors were recruited in this study, of whom 14,300 (87.4%) donated only once during this study (single, non-duplicated blood donors), while 2067 (12.6%) were repeated or duplicated. The overall prevalence of HBsAg and anti-HBcAb was 2.4% and 10.8%, respectively. Among single non-duplicated blood donors, HBsAg and Anti-HBcAb were 2.3% and 10.6% and 3.0% and 12.5% for repeated blood donors, respectively. There were statistically significant differences between HBsAg and Anti-HBcAb in terms of donor type and testing techniques. Conclusion The seroprevalence of HBsAg and anti-HBcAb among the blood donors was 2.0% and 10.3%, respectively. The ECL technique is more sensitive, has a lower error rate, and shows an advantage over the manual EIA technique. Duplicated blood donors influence the accuracy of the seroprevalence of HBsAg and anti-HBcAb.

show abstract

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

“… 14 , 35 , 49 A recent study revealed prevalence rates of HBsAg and Anti-HBc Ab among the different age groups fairly similar to that study conducted in Sana’a city, Yemen. 16 …”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Updated Seroprevalence of Hepatitis B Surface Antigen and Anti-Hepatitis Core Antibody Among Blood Donors in Yemen

Alzubiery¹,

Alharazi²,

Alcantara³

et al. 2022

IDR

View full text Add to dashboard Cite

show abstract

Reported Seroprevalence of Transfusion-Transmitted Infections in Voluntary and Replacement Donors

Rasool

Khan

Malik

et al. 2023

Transfusion Medicine Reviews

View full text Add to dashboard Cite

Yemen'de Hepatit C Virüsü Epidemiyolojisi: Sistematik İnceleme

Almahbashi¹

2021

Akademik Gastroenteroloji Dergisi

View full text Add to dashboard Cite

tality of HCV strains healthcare systems worldwide, the Direct-acting antivirals (DAAs) give promising prospects to clear HCV infection and reduce HCV disease burden in the soon future (6). Whereas the elimination of hepatitis C virus by 2030 is a global goal for the World Health Organization (WHO). The epidemiology of hepatitis C in Yemen is still not well described, and it needs to define the prevalence in different populations and define the areas of a future epidemiological study in Yemen which are the objectives of this systematic review (7,8). Bacground and Aims:To identify and well-characterize the prevalence of hepatitis C virus infection in different populations in Yemen. Also, to determine the future epidemiological study areas in Yemen. Materials and Methods: A systematic review was conducted with the use of the PRISMA guidelines. Between 1980 to 2020, a comprehensive search was done for any epidemiological data on hepatitis C in Yemen that were conducted in each PubMed, web of Science, Scopus, and Google Scholar. Results: Forty-nine (49) studies were matching the inclusion and exclusion criteria from the four databases. After analyzing these 49 studies we found that in the general group of the population the prevalence was ranged between 0.07%-8.5%. Where the highest prevalence was in pregnant women (up to 8.5%) then the public (up to 6%) then blood donors and children up to 3% and 2.8% respectively. In the intermediate-risk group, hepatitis C virus infection prevalence was ranged between 1.03%-3.5% where all population was from the health department workers. In the high-risk group, the range was between 6.4%-62.7%, and the highest prevalence was recorded in liver disease patients. In the patient's group the range of hepatitis C virus infection prevalence was between 0%-46%, while the sickle cell anemia patients were the lowest prevalence the chronic renal failure patients had the highest prevalence. Conclusion: This systemic review demonstrates a high prevalence of hepatitis C infection in Yemen. There is also a need to expand the scope of research and pay attention to new research groups and other cities to get a more comprehensive idea of the prevalence of the hepatitis C virus in Yemen.

show abstract

Sero-Prevalence of HBs Ag, HCV and HIV among Blood Donors in Three Blood Bank Centers in Sana'a city: Yemen

Cited by 4 publications

References 11 publications

Updated Seroprevalence of Hepatitis B Surface Antigen and Anti-Hepatitis Core Antibody Among Blood Donors in Yemen

Updated Seroprevalence of Hepatitis B Surface Antigen and Anti-Hepatitis Core Antibody Among Blood Donors in Yemen

Reported Seroprevalence of Transfusion-Transmitted Infections in Voluntary and Replacement Donors

Yemen'de Hepatit C Virüsü Epidemiyolojisi: Sistematik İnceleme

Contact Info

Product

Resources

About