Sero-epidemiological study of SARS-CoV-2 infection among healthcare personnel in a healthcare department

Gras-Valentí, Paula; Chico-Sánchez, Pablo; Algado-Sellés, Natividad; Gimeno-Gascón, María Adelina; Mora-Muriel, Juan Gabriel; Jiménez-Sepúlveda, Natali Juliet; Gómez-Sotero, Isel Lilibeth; Montiel-Higuero, Inés; Sánchez‐Paya, José; Rodríguez-Díaz, Juan Carlos

doi:10.1016/j.eimce.2021.05.008

Cited by 3 publications

(2 citation statements)

References 12 publications

(13 reference statements)

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“…In a study exploring the prevalence of IgG antibodies against SARS-CoV-2 among healthcare personnel in a health facility, the overall prevalence for presence of anti-SARS-CoV-2 IgG antibodies was identified to be 6.6% (95% CI: 5.8-7.3). According to the age group, with the prevalence varying between 5.2% (95% CI: 3.5-7.0) in the 60-64 age group and 10.8% (95% CI: 2.5-19.1) in the group aged 65 and over, it was revealed that there was no significant difference based on age group [13]. In our study, absenteeism was observed most frequently in the 30-39 age group with a rate of 30.2%.…”

Section: U N C O R R E C T E D a U T H O R P R O O Fmentioning

confidence: 93%

An assessment on loss of workforce due to COVID-19 among healthcare personnel: A university hospital experience

Pirdal

Toplu

Esen

et al. 2022

WOR

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BACKGROUND: Healthcare personnel are among the COVID-19 risk groups. For this reason, increased absence from work affects the loss of labor. OBJECTIVE: This study aimed to evaluate the workforce loss amongst health personnel working in our hospital due to COVID-19 in a one-year period. METHODS: Workforce loss of healthcare workers was assessed via absenteeism and life expectancy. Loss of workforce for COVID-19 PCR positive or PCR negative but CT findings compatible with COVID-19 and personnel with high-risk exposure for COVID-19 were determined with absenteeism. Healthcare personnel who passed away due to COVID-19 was determined with the consideration of the retirement age and expected life years. RESULTS: Total lost time from work was 14635 days (excluding deaths). Loss of workforce rates resulting from COVID-19 positivity for male employees was greater in comparison to the results for females (p = 0.018). High-risk exposure of healthcare personnel working in clinical sciences was higher than those in other departments (p < 0.001). Total loss in workforce for 3 people passed away was 14 years 5 months, and total life expectancy was 64 years. Healthcare personnel under the age of 40 had less absenteeism than those over 40 years (p < 0.001). CONCLUSIONS: It was observed that all occupational groups working at the hospital were impacted by COVID-19. The two most important factors that influenced absenteeism were the reason for being affected (positivity and high risk) and age. Absenteeism and daily case tracing of healthcare personnel working on the frontlines will aid in both the pandemic control and management of workload for those left behind.

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Section: U N C O R R E C T E D a U T H O R P R O O Fmentioning

confidence: 93%

An assessment on loss of workforce due to COVID-19 among healthcare personnel: A university hospital experience

Pirdal

Toplu

Esen

et al. 2022

WOR

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“…A cross-sectional study by Gras-Valenti et al, conducted in tertiary hospital and 12 primary care centers in Alicante, revealed that among 4 179 HCWs, the overall prevalence of SARS-CoV-2 IgG antibodies was 6.60% (8.70% in physicians, 3.20% among staff members not associated with healthcare). The occupation was the only factor significantly associated with the presence of SARS-CoV-2 antibodies [25]. In a study by Moncunill et al on seroprevalence and antibody kinetics, conducted in Barcelona during the COVID-19 spring 2020 pandemic peak, the prevalence of SARS-CoV-2 among 578 HCWs was 11.20%.…”

Section: Group: Sweden Belgium Spain -Epidemiological Strategies and ...mentioning

confidence: 95%

SARS-CoV-2 antibody screening in healthcare workers: lessons learned from the first months of COVID-19 outbreak in Europe. Significance of serology testing for effective pandemic management and reduction of the occupational risk

Burdalska

Konka

Woroszyło

et al. 2022

Polish Journal of Public Health

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Introduction. Detected in 2019 in Wuhan, China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing a coronavirus disease 2019 (COVID-19), has changed almost all aspects of human lives. It has had an enormous impact on societies, economies and politics across the world. Nevertheless, first and foremost, it has led to a global health crisis on an unprecedented scale. Since the pandemic’s beginning, one of the greatest global challenges has been to stop the spread of infection among healthcare workers (HCWs). As a front-line fighters, they are at higher risk of contracting SARS-CoV-2 than other professions. Aim. The study aimed to determine the role of serological testing among HCWs by analyzing screening results for the presence of SARS-CoV-2 antibodies in this group in 12 European countries during the first wave of the pandemic. Material and methods. Pubmed, MEDLINE, Web of Science, Google Scholar, and WHO COVID-19 databases were searched for studies on screening among HCWs using immunoassays or chemiluminescence assays for preventive purposes and determining the percentage of HCWs with acquired immunity to SARS-CoV-2. The number of 30 papers were selected. Immunoglobulin G (IgG) percentage was analyzed, and determination of immunoglobulin A (IgA) and immunoglobulin M (IgM) antibodies and their diagnostic usefulness. Results. The screening results of HCWs were juxtaposed with epidemic situation of that time and public health measures in given country. Conclusion. Introduction of routine serological testing of HCWs could be a valuable strategy to monitor the occupational risk in this group and effectiveness of local epidemic management strategies.

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Efficacy and Effectiveness of SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis

Ghazy

Ashmawy²,

Hamdy

et al. 2022

Vaccines

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The coronavirus disease 2019 (COVID-19) pandemic has threatened global health and prompted the need for mass vaccination. We aimed to assess the efficacy and effectiveness of COVID-19 vaccines to prevent mortality and reduce the risk of developing severe disease after the 1st and 2nd doses. From conception to 28 June 2021, we searched PubMed, Cochrane, EBSCO, Scopus, ProQuest, Web of Science, WHO-ICTRP, and Google Scholar. We included both observational and randomized controlled trials. The pooled vaccine efficacy and effectiveness following vaccination, as well as their 95 percent confidence intervals (CI), were estimated using the random-effects model. In total, 22 of the 21,567 screened articles were eligible for quantitative analysis. Mortality 7 and 14 days after full vaccination decreased significantly among the vaccinated group compared to the unvaccinated group (OR = 0.10, ([95% CI, 0.04–0.27], I2 = 54%) and (OR = 0.46, [95% CI, 0.35–0.61], I2 = 0%), respectively. The probability of having severe disease one or two weeks after 2nd dose decreased significantly (OR = 0.29 [95% CI, 0.19–0.46], I2 = 25%) and (OR = 0.08 [95% CI, 0.03–0.25], I2 = 74%), respectively. The incidence of infection any time after the 1st and 2nd doses diminished significantly (OR = 0.14 [95% CI, 0.07–0.4], I2 = 100%) and (OR = 0.179 [95% CI, 0.15–0.19], I2 = 98%), respectively. Also, incidence of infection one week after 2nd dose decreased significantly, (OR = 0.04, [95% CI (0.01–0.2], I2 = 100%). After meta-regression, the type of vaccine and country were the main predictors of outcome [non-mRNA type, ß = 2.99, p = 0.0001; country UK, ß = −0.75, p = 0.038; country USA, ß = 0.8, p = 0.02]. This study showed that most vaccines have comparable effectiveness, and it is purported that mass vaccination may help to end this pandemic.

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Sero-epidemiological study of SARS-CoV-2 infection among healthcare personnel in a healthcare department

Cited by 3 publications

References 12 publications

An assessment on loss of workforce due to COVID-19 among healthcare personnel: A university hospital experience

An assessment on loss of workforce due to COVID-19 among healthcare personnel: A university hospital experience

SARS-CoV-2 antibody screening in healthcare workers: lessons learned from the first months of COVID-19 outbreak in Europe. Significance of serology testing for effective pandemic management and reduction of the occupational risk

Efficacy and Effectiveness of SARS-CoV-2 Vaccines: A Systematic Review and Meta-Analysis

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