Serious renal dysfunction after percutaneous coronary interventions can be predicted

Brown, Jeremiah R.; DeVries, James T.; Piper, Winthrop D; Robb, John F.; Hearne, Michael J.; Lee, Peter M Ver; Kellet, Mirle A; Watkins, Mathew W.; Ryan, Thomas J.; Silver, Marc T.; Ross, Cathy S.; MacKenzie, Todd A.; O’Connor, Gerald T.; Malenka, David J.

doi:10.1016/j.ahj.2007.10.007

Cited by 129 publications

(96 citation statements)

References 31 publications

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“…In 11,141 consecutive patients from northern New England undergoing PCI without dialysis, preprocedural creatinine (37%), congestive heart failure (24%), and diabetes (15%) accounted for 76% of the predictive ability of the model of serious renal dysfunction. [32] In 936 Chinese patients scheduled for elective PCI, the incidence of CIN was more common in the abnormal group (serum creatinine > 1.5 mg/dL) than in the normal group (6.52% vs. 37.68%, p < 0.001). [33] Predictors of CIN were as follows: age ≥ 70, contrast volume ≥ 320 ml, diabetes mellitus, and peripheral arterial disease.…”

Section: Discussionmentioning

confidence: 99%

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Urinary and Serum Biomarkers after Cardiac Catheterization in Diabetic Patients with Stable Angina and without Severe Chronic Kidney Disease

Małyszko

Bachórzewska−Gajewska

Poniatowski

et al. 2009

Renal Failure

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Background/Aims. Different serum and urinary biomarkers have been recently proposed to serve as markers of acute kidney injury. We tested the hypothesis whether NGAL and other biomarkers could represent an early biomarker of contrast nephropathy (CIN) in diabetic patients with normal serum creatinine undergoing cardiac catheterization in comparison with nondiabetic patients. Methods. Serum, urinary NGAL, cystatin C, urinary kidney injury molecule-1 (KIM-1), interleukin-18 (IL-18), and liver-type fatty acid binding protein (L-FABP) were evaluated before and 2, 4, 8, 24, and 48 hours after cardiac catheterization using commercially available kits. Results. In both groups we found a significant rise in serum NGAL after 2, 4, and 8 hours, and in urinary NGAL and IL-18 after 4, 8, and 24 hours after cardiac catheterization. Serum cystatin C increased significantly 8 hours, reaching peak 24 hours after cardiac catheterization in both groups, and then decreased after 48 hours. L-FABP and KIM-1 increase significantly after 24 and 48 hours after cardiac catheterization. Conclusions. CIN was similarly prevalent in both diabetic and non-diabetic patients undergoing cardiac catheterization. NGAL seems to be a potential early marker for nephrotoxicity and predictor of contrast nephropathy. It is particularly important in the upcoming setting of short-time hospitalizations for cardiac catheterization.

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Section: Discussionmentioning

confidence: 99%

“…[37] Urinary assay requires only 150 μl of urine, and results are available within 35 minutes. [32] It could be particularly useful in patients with impaired kidney function, a population particularly prone to rapid deterioration of renal function. It might enable prompt intervention in this clinical setting.…”

Section: Discussionmentioning

confidence: 99%

Urinary and Serum Biomarkers after Cardiac Catheterization in Diabetic Patients with Stable Angina and without Severe Chronic Kidney Disease

Małyszko

Bachórzewska−Gajewska

Poniatowski

et al. 2009

Renal Failure

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“…8,9) Since, in our daily practice, as in this study, we avoid using contrast media in patients with diabetes mellitus, who has congestive heart failure and estimated glomerular filtration rate <60 mL/min/1.72m 2 , which is thought to be a risk factor of contrast media inducing acute kidney injury. 10,11) Many reports suggest the usefulness and feasibility of PDE in assessing ITA graft function. [5][6][7] Those many reports recommended adopting mean flow, diastolic flow, VTI or DF of ITA graft to assess its function, which we adopted in this study, as well.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of ITA Graft Function Using CT Angiography

Hashimoto

Yamauchi

Naraoka³

et al. 2012

Annals of Vascular Diseases

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“…Investigations at other institutions are planned. In addition, prevention is the most important consideration for CIAKI, and the usefulness of risk scores predicting the development CIAKI has been reported; 5 however, no prospective studies have been performed to date, and therefore, they will be necessary in the future. Furthermore, the development of novel treatments to prevent CIAKI is also required.…”

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confidence: 99%