Serious Hazards of Transfusion (SHOT)

Shivaram, C

doi:10.5005/jp/books/11332_12

Cited by 1 publication

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“…1 Blood is costly, time consuming to administer (2 h of nursing time per transfusion in our centre) and associated with a risk of adverse events such as increased exposure to allogenic blood and formation of allo-antibodies, transfusion related reactions and iron toxicity that may then lead to venesections afterwards. 11 In United Kingdom, at present, each standard red cell unit costs £145.99 and cost of administration is around £49.00. 12,13 We have demonstrated to save more than £63500.00 and more than 650 h of nursing time in the period of 9 months post-change.…”

Section: Statisticsmentioning

confidence: 99%

Real world reduction in red cell transfusion with restrictive transfusion threshold in haematology inpatients

Pervaiz

Dhanapal

Pillai

et al. 2023

Transfusion Medicine

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Objectives The aim of this study was to assess the reduction in red cell transfusions following a change in the red cell transfusion threshold for haematology inpatients from 80 to 70 g/L. Background Haematology patients are among the high users of red blood cells. We reduced the threshold for transfusion of haematology inpatients to 70 g/L. This was based on evidence provided by randomised controlled trial published in 2020 that showed restrictive transfusion is non‐inferior to liberal transfusion. Method We assessed red cell transfusions for haematology inpatients at Oxford University Hospitals NHS Foundation Trust for 9 months before and 9 months after a change in red cell transfusion threshold from 80 to 70 g/L. Results After the change in threshold to 70 g/L or less from 80 g/L, the median number of red cell transfusions per month reduced to 88 from 111. This was a 23% reduction in the total number of red cells administered per month. Conclusion These results show the real‐world reductions in transfusion that can be made by putting local transfusion guidelines in line with the international recommendations. This is of particular importance at a time of national blood shortage.

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Section: Statisticsmentioning

confidence: 99%