“…Furthermore, B-13 cells do not require an extensive array of recombinant growth factors and/or other signalling inhibitor treatments to direct them to become hepatocytes. Exposure to a single glucocorticoid hormone is all that is required ( Shen et al, 2000 , Wallace et al, 2011 ). Critically, in contrast to stem cell-derived hepatocyte-like cells which generally only form a foetal level of hepatic differentiation, B-13/H cells express many adult hepatocyte genes at adult hepatocyte levels ( Marek et al, 2003 , Fairhall et al, 2013a , Fairhall et al, 2016 ).…”