Serine racemase deletion alters adolescent social behavior and whole-brain cFos activation
Stephanie E. Brown,
Ziyi (Zephyr) Wang,
Emily L. Newman
et al.
Abstract:BackgroundNeurodevelopmental disorders (NDDs) can cause debilitating impairments in social cognition and aberrant functional connectivity in large-scale brain networks, leading to social isolation and diminished everyday functioning. To facilitate the treatment of social impairments, animal models of NDDs that link N- methyl-D-aspartate receptor (NMDAR) hypofunction to social deficits in adulthood have been used. However, understanding the etiology of social impairments in NDDs requires investigating social ch… Show more
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