Series of Poly(4‐vinylpyridine) Containing Quaternary Alkyl bromides: Synthesis and Determination Percentage of Quaternization

Abstract

Summary: In this study, we focus on the synthesis series of poly(4-vinylpyridine) (P4VP) containing quaternary alkyl bromides. The poly(4-vinylpyridine) (P4VP) was synthesized by conventional radical copolymerization and then the P4VP was quaternized by alkyl bromides containing chains consisting of 5 and 10 carbon atoms. Two copolymers series with three degrees of polymerization have been synthesized, the first poly[N-isopentyl(4-vinylpyridinium)] bromide P4VPIPBr (I); (II); (III) and the second poly[N-decyl(4-vinylpyridinium)] bromide P4VPBrD (I); (II); (III). The following techniques have been used to characterize the structure and composition of the cationic copolymers (P4VPIPBr) and (P4VPBrD), HNMR, conductimetry and viscometry.

Core-Cross-Linked Micelles Made by RAFT Polymerization with a Polycationic Outer Shell Based on Poly(1-methyl-4-vinylpyridinium)

“…In this respect, we note that vinylpyridinium monomers can undergo free radical polymerization, − but the kinetic behavior is peculiar with a high reaction order in the monomer (e.g., 2.7), and thus, the polymerization is too slow in dilute solutions. Poly­(vinylpyridinium) polymers have also been obtained by free radical polymerization of vinylpyridine, followed by quaternization. , The RAFT polymerization of a vinylpyridium salt has apparently never been reported, although it has been shown that a controlled RAFT polymerization takes place for other cationic monomers, for instance, a styrene containing a benzylic pyridium substituent in the para position, CH 2 CH–C 6 H 4 -4-CH 2 C 5 H 5 N + Cl – . Additional control experiments have shown the absence of reactivity between the RAFT agent and the monomer, as well as between the RAFT agent and MeI.…”

Stimuli-Responsive Triblock Terpolymer Conversion into Multi-Stimuli-Responsive Micelles with Dynamic Covalent Bonds for Drug Delivery through a Quick and Controllable Post-Polymerization Reaction

“…In addition to its intrinsic pH responsivity, P4VP is suitable for post-polymerization modifications through the quaternization of the nitrogen atom via multiple types of halogenated molecules [ 32 , 33 , 34 , 35 ]. The possibility of using a broad range of compounds as a quaternization agent opens many opportunities for tuning the system as desired.…”