“…For this reason, all health and exercise organizations such as the ACSM, the WHO, and the CDC recommend the systematic participation of middle-aged and older individuals in combined exercise programs consisting of cardiovascular and neuromuscular activities as the most effective “non-pharmacological” intervention for counteracting the harmful effects of a sedentary lifestyle and aging [ 4 , 5 , 6 ]. In this context, during the last few decades, different sports and health professionals all over the world have focused on the design, implementation, and evaluation of different serial and integrated combined exercise programs using various activities and training means [ 13 , 14 , 23 , 24 , 26 , 28 , 49 , 50 , 51 , 52 , 53 , 54 , 55 ]. Although chair-based exercise programs have gained popularity as an alternative mode of exercise for improving health, functional capacity, and physical fitness, especially in older and frail individuals [ 7 , 8 , 9 , 10 , 11 , 12 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ], only a few studies have examined the effects of chair-based exercise programs in healthy middle-aged individuals [ 13 , 14 ].…”