Serial Histologic Effects of Rat Submaxillary and Sublingual Salivary Gland Duct and Blood Vessel Ligation

Standish, S. Miles; Shafer, William G.

doi:10.1177/00220345570360060801

Cited by 132 publications

(47 citation statements)

References 6 publications

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“…La théo-rie vasculaire est étayée par plusieurs études expérimentales chez l'animal. Les études chez le rat montrent que la ligature des artères et/ou des canaux des glandes salivaires, induit des modifications histologiques similaires à celles de la SMN [134,135]. Les caractéristiques morphologiques de la SMN ont éga-lement été observées au cours d'études expérimentales induisant des tumeurs dans les glandes salivaires du rat après l'injection ou l'implantation de diméthylbenzanthracène [134,136,137].…”

Section: Discussionunclassified

La sialométaplasie nécrosante : revue systématique de la littérature

Aubies-Trouilh¹,

Fricain²

2012

Med Buccale Chir Buccale

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Résumé -Objectif :Répertorier les caractéristiques épidémiologiques, étiopathogéniques, cliniques, histologiques et thérapeutiques de la sialométaplasie nécrosante (SMN). Results: NSM is an uncommon benign disease of salivary glands. Usually, NSM affects the minor salivary glands of the hard palate. It occurs primarily in adults, NSM is manifested by a sharply demarcated crater-like palatal ulcer. Although the etiology is uncertain, the lesion heals spontaneously. Conclusion: Dental surgeon has to know this lesion because of the risk of histological and clinical confusion with malignant lesions which may lead to mutilating radical treatment.

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Section: Discussionunclassified

La sialométaplasie nécrosante : revue systématique de la littérature

Aubies-Trouilh¹,

Fricain²

2012

Med Buccale Chir Buccale

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“…This is supported by the observation that ligation of the arterial supply to major salivary glands in rodents may result in a similar histopathological picture. 15,16 The disease is also seen in sickle cell disease, which can cause infarction and the vasculopathies, Buerger's disease and Raynaud's disease or phenomenon; conditions which both predispose to ischaemia. 17,18 Other ischaemic predisposing factors include: vascular damage due to trauma from intubation 19 or fellatio, 5 local anaesthetic needles, 6 or chronic vomiting.…”

Section: Aetiopathogenesismentioning

confidence: 99%

Necrotizing sialometaplasia: An unusual bilateral presentation associated with antecedent anaesthesia and lack of response to intralesional steroids. Case report and review of the literature

et al. 2004

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Necrotizing sialometaplasia is a self-limiting, variably ulcerated benign process affecting minor salivary glands. Accurate histological diagnosis is paramount, as it has been mistaken for malignancy, which has resulted in excessively aggressive and unnecessary radical surgery. A unique case of bilateral necrotizing sialometaplasia, presenting with anaesthesia of the greater palatine nerves, is described. An attempt at active therapy with intralesional steroids had no effect on the course of the condition.

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“…These experiments were carried out after atrophy of the secretory cells elicited by duct ligation 15 days before the experiment (Standish & Shafer, 1957). In these atrophied salivary glands, the secretory responses to adrenoceptor or cholinoceptor agonists are abolished at a time when there are no changes in either the cholinergic or the noradrenergic innervation (Filinger, Langer, Perec & Stefano, 1977).…”

Section: A)mentioning

confidence: 99%