Serial Fiberoptic Bronchoscopic Observations of Endobronchial Tuberculosis Before and Early After Antituberculosis Chemotherapy

Kim, Young Hoon; Kim, Hyeon Tae; Lee, Kyung Soo; Uh, Soo Taek; Cung, Yeon Tae; Park, Choon-Sik

doi:10.1378/chest.103.3.673

Cited by 71 publications

(42 citation statements)

References 17 publications

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“…These patients then showed a stable clinical course for a median of 36 months. Considering the natural fibrotic process that occurs after endobronchial TB by M. tuberculosis infection [2,21], stents should be replaced at least once a year.…”

Section: Discussionmentioning

confidence: 99%

“…P ost-tuberculosis tracheobronchial stenosis (PTTS) is the most common cause of benign tracheobronchial stenosis in tuberculosis (TB) endemic areas, such as South Korea, where the prevalence of pulmonary TB is 1.0% [1,2]. Even when taking effective anti-TB medication, some cases of PTTS may progress to obstruction of major airways [1,2].…”

mentioning

confidence: 99%

“…Even when taking effective anti-TB medication, some cases of PTTS may progress to obstruction of major airways [1,2]. Surgical resection and reconstruction after the eradication of Mycobacterium tuberculosis has been the preferred treatment for most patients with PTTS [1, 2].…”

mentioning

confidence: 99%

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Use of silicone stents for the management of post-tuberculosis tracheobronchial stenosis

Ryu¹,

Kim²,

Yu³

et al. 2006

European Respiratory Journal

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The role of bronchoscopic management in post-tuberculosis tracheobronchial stenosis is not well defined. To investigate the role of bronchoscopic intervention, including silicone stenting, in the management of post-tuberculosis tracheobronchial stenosis, the current retrospective study was conducted at a tertiary referral hospital.Under rigid bronchoscopy, 80 patients underwent ballooning, neodymium-yttrium aluminium garnet laser resection and/or bougienation as first-line methods of airway dilatation between January 2000 and December 2003 inclusive, and were followed for a median of 41 months.Silicone stents were required in 75 out of 80 (94%) patients to maintain airway patency. Bronchoscopic intervention provided immediate symptomatic relief and improved lung function in 88% of the patients. After airway stabilisation, stents were removed successfully in 49 out of 75 (65%) patients at a median of 14 months post-insertion. Three patients out of 75 (4%) eventually underwent surgical management. Acute complications included: excessive bleeding (n51); pneumothorax (n55); and pneumomediastinum without mortality (n52). Stent-related late complications, such as migration (51%), granuloma formation (49%), mucostasis (19%) and restenosis (40%), were controllable during a median follow-up of 41 months.In conclusion, bronchoscopic intervention, including silicone stenting, could be a useful and safe method for treating post-tuberculosis tracheobronchial stenosis.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Use of silicone stents for the management of post-tuberculosis tracheobronchial stenosis

Ryu¹,

Kim²,

Yu³

et al. 2006

European Respiratory Journal

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“…It has been reported that AFB exam in cases with ET could be negative as in the presented case (10). Kim et al (10) found that approximately one third of ET cases had negative culture results in their study population.…”

Section: Discussionmentioning

confidence: 84%

Endobronchial tuberculosis mimicking lymphoma

Uyar¹,

Mete²,

Filiz³

et al. 2011

Gaziantep Med J

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Endobronchial tuberculosis may present with different clinical pictures. We presented a 55 year old patient with complaint of cough. She had palpable supraclavicular and cervical lymph nodes. Thorax CT revealed multiple conglomerated mediastinal lymph nodes. Multiple swollen mucosal nodularities were observed on bilateral endobronchial area during fiberoptic bronchoscopy. Although acidfast bacilli were negative in bronchial lavage fluid, biopsies obtained from the endobronchial nodules revealed caseous granulomatous inflammation compatible with tuberculosis. Improvement was achieved one month following antituberculosis therapy. This case report shows the importance of fiberoptic bronchoscopy in the differential diagnosis of subjects present with multiple mediastinal lymphadenopathies especially in populations where incidence of tuberculosis is high. Keywords: Bronchoscopy; lymphoma; tuberculosis Özet Endobronşial tuberküloz farklı klinik tablolarda karşımıza çıkabilir. Biz bu yazıda öksürük şikayeti olan 55 yaşındaki bir kadın hastayı sunduk. Hastanın palpe edilebilen supraklaviküler ve servikal lenf nodları mevcuttu. Toraks BT'de multipl konglomere mediastinal lenf nodları mevcuttu. Fiberoptik bronkoskopik incelemede ise yaygın mukozadan kabarık mukozal nodülariteler her iki akciğer alanlarında tespit edildi. Bronş lavajı ARB'si negatif olmasına rağmen endobronşial alandan alınan biyopsiler tüberküloza uyan şekilde kazeöz granulomatöz inflamasyonla uyumluydu. Tüberküloz tedavisi başlandıktan bir ay sonra düzelme tespit edildi. Bu olgu sunumu özellikle tüberküloz insidansının yüksek olduğu populasyonlarda multipl mediastinal lenfadenopatilerin ayırıcı tanısında fiberoptik bronkoskopinin önemini göstermektedir.

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“…The pathogenesis of endobronchial tuberculosis is not yet fully established. However, proposed mechanisms include direct implantation of tubercle bacilli into the broncus from an adjacent pulmonary parenchymal lesion, direct airway infiltration from an adjacent tuberculous mediastinal lymph node, erosion and protrusion of an intrathoracic tuberculous lymph node into bronchus, hematogenous spread, and extension to the peribronchial region by lymphatic drainage (2,3,9).…”

Section: Discussionmentioning

confidence: 99%

Bilateral multiple tumor-like endobronchial tuberculosis, diagnosed with bronchoscopic examination

Kont

Oktay²,

Sevgi³

et al. 2011

Tuberk Toraks

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Serial Fiberoptic Bronchoscopic Observations of Endobronchial Tuberculosis Before and Early After Antituberculosis Chemotherapy

Cited by 71 publications

References 17 publications

Use of silicone stents for the management of post-tuberculosis tracheobronchial stenosis

Use of silicone stents for the management of post-tuberculosis tracheobronchial stenosis

Endobronchial tuberculosis mimicking lymphoma

Bilateral multiple tumor-like endobronchial tuberculosis, diagnosed with bronchoscopic examination

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