Sequential use of Foley catheter with misoprostol for second trimester pregnancy termination in women with and without caesarean scars: a prospective cohort study

Velipaşaoğlu, Melih; Ozdemir, Cem Yagmur; Ozek, Burcu; Ayaz, Reyhan; Tanir, H. Mete

doi:10.1080/14767058.2017.1293037

Cited by 8 publications

(2 citation statements)

References 12 publications

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“…It was reported that Foley catheter procedure in addition to misoprostol was efficient and safe in cases which underwent cesarean. [24] In our studies, 100 cases had cesarean section history. We did not find any significant difference between scarred and unscarred uterines in terms of termination durations.…”

Section: Discussionmentioning

confidence: 60%

The analysis of the termination of pregnancies at and after ten weeks of gestation – a monocenter study

Baran¹,

Alemdaroğlu²,

Durdağ³

et al. 2019

Perinatal J

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On hafta ve üzeri gebelik terminasyonlar›n›n analizi-Tek merkezli çal›flma Amaç: Klini¤imizde yap›lm›fl olan 10 hafta ve üzeri gebelik termi-nasyonlar›n›n endikasyonlar›n› ve obstetrik özelliklerini inceleyerek, bu olgular› daha iyi yönetebilmeyi ve do¤ru yaklafl›mlar› gelifltirebilmeyi amaçlad›k. Yöntem: Ocak 2012-Ocak 2019 aras›nda klini¤imizde gerçekleflmifl 379 terminasyon olgusunun maternal verileri, obstetrik özellikleri ve endikasyonlar› de¤erlendirildi. Endikasyonlar; maternal nedenler, amniyotik s›v› anomalileri, izole yap›sal, çoklu konjenital ve genetik bozukluklar olarak grupland›r›ld›. Gruplar özelliklerine göre s›n›fland›r›ld› ve kendi aralar›nda karfl›laflt›r›ld›. Bulgular: Ortalama yafl 30.2±6, ortalama gebelik haftas› 17.4±3.5, ortalama terminasyon süresi 16.4±14.5 saatti. En s›k amniyotik s›-v› anomalileri nedeniyle terminasyon yap›ld›¤› izlendi (n=126, %33.2). Fetal nedenler içerisinde en s›k izole yap›sal anomaliler (n=114, %30.1) tespit edildi. Santral sinir sistemi anomalileri en çok görülen izole yap›sal anomaliler idi (n=60, %15.8). Terminas-yonlar›n 25/379'u (%6.6) maternal nedenli idi. Genetik bozukluklar için invaziv tetkik istenme oran› %49.6 (n=197), yap›lma oran› %31.7 (n=120) idi. En s›k trizomi 21 (n=39, %55.7) olmak üzere kromozomal anomali 69 (%18.2) olguda tespit edildi. Kromozomal anomalilerin daha ileri maternal yafl ve daha erken gebelik haf-talar›nda tespit edildi¤i izlendi. ‹zole yap›sal ve çoklu konjenital anomalilerin ise daha genç yaflta ve daha ileri gebelik haftalar›nda saptand›¤› görüldü (özellikle kardiyak ve ürogenital anomaliler) (maternal yafl, p=0.002; gebelik haftas›, p<0.001). Sonuç: Terminasyon olgular›n›n yönetiminde fetal ve maternal nedenlerin ve terminasyon komplikasyonlar›n›n analizi, takip eden gebeliklerin tan› ve terminasyon süreçlerinin yönetiminde örnek olacakt›r. Gebelik terminasyonlar›n›n etik, psikolojik, ekonomik ve yasal boyutlar›n›n dikkate al›nmas›, aile ile hekim iflbirli¤i içerisinde bu konuda standart yaklafl›mlar›n oluflturulmas›nda etkili olaca¤› görüflündeyiz.

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Section: Discussionmentioning

confidence: 60%

The analysis of the termination of pregnancies at and after ten weeks of gestation – a monocenter study

Baran¹,

Alemdaroğlu²,

Durdağ³

et al. 2019

Perinatal J

View full text Add to dashboard Cite

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“…However the 6 hour expulsion rate (36.4% versus 0%, p=0.001) and 12 hour expulsion rate (56.36% versus 3.6%, p=0.001) were significantly higher in the mifepristone -misoprostol group. 16 Not even a single women expelled within 6 hours in the mifepristone foley EAS group whereas 20 out of the 55 expelled within this time period in the mifepristonemisoprostol group. Similarly 31 women out of the 55 in the mifepristone-misoprostol group expelled within 12 hours whereas only 2 women out of the 55 in the second group expelled within this period.…”

Section: Figmentioning

confidence: 98%

Comparison of effectiveness of mifepristone misoprostol combination versus mifepristone Foley EAS (Extra-amniotic instillation of saline) combination in second trimester pregnancy termination

Kusumam¹,

Khan²,

V.G³

2020

IJOGR

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Second trimester medical abortion with mifepristone followed by misoprostol is effective and is associated with considerably shorter induction abortion interval. This study is a comparison of the effectiveness, safety profile and side effects of mifepristonemisoprostol and mifepristone-Foley's EAS combinations in second trimester termination. The patients were grouped into two, first group received oral mifepristone 200 mg followed by vaginal misoprostol 800 mcg after 48 hours and then 400 mcg misoprostol vaginally 3 hourly up to a maximum of 4 further doses. Second group were induced with oral mifepristone 200 mg followed by extra amniotic saline instillation through a Foley's catheter after 48 hours. The success rates were comparable between the two groups. But the 6 hour expulsion rates (36.4% Vs 0%) as well as 12 hour expulsion rates (56.36% Vs 3.6%)(p value=0.001) were significantly high in mifepristonemisoprostol group compared to mifepristone-Foley EAS group. Mean induction abortion interval was shorter in the first group (14.64hrs vs 18.4hrs)(p=0.026).But the incidence of complaints after administration of misoprostol was significantly high. 7 patients from Group 1 and 5 patients from Group 2 required surgical evacuation for retained placenta. The study revealed that mifepristone-Foley's EAS induction can be used as an effective alternative to mifepristone-misoprostol combination with similar success rates and significantly reduced side effects but with significantly increased induction abortion interval. The results of this study can be extrapolated to cases where prostaglandins are contraindicated like in previous cesarean section cases.

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Termination of pregnancy for medical indications—in singleton pregnancy

Schild

Morfeld

2020

Gynäkologe

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Sequential use of Foley catheter with misoprostol for second trimester pregnancy termination in women with and without caesarean scars: a prospective cohort study

Abstract: Sequential use of misoprostol and Foley catheter is safe and effective in second trimester pregnancy termination for patients with and without CS scars.

Cited by 8 publications

References 12 publications

The analysis of the termination of pregnancies at and after ten weeks of gestation – a monocenter study

The analysis of the termination of pregnancies at and after ten weeks of gestation – a monocenter study

Comparison of effectiveness of mifepristone misoprostol combination versus mifepristone Foley EAS (Extra-amniotic instillation of saline) combination in second trimester pregnancy termination

Termination of pregnancy for medical indications—in singleton pregnancy

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