Sequential perioperative lactate determination. Physiological and clinical implications

Waxman, Kenneth; Nolan, Lorene S.; Shoemaker, William C.

doi:10.1097/00003246-198202000-00005

Cited by 60 publications

(14 citation statements)

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“…The former alternative explanation cannot be excluded. However, no evidence of hepatic dysfunction was detected in any of our patients perioperatively, and most previous reports have not considered this explanation important [5,13,19]. Regional ischaemia may play a partial role in the development of the acidosis.…”

Section: Discussioncontrasting

confidence: 55%

What factors are associated with hyperlactatemia after cardiac surgery characterized by well-maintained oxygen delivery and a normal postoperative course? A retrospective study

Inoue¹,

Kuro²,

Furuya³

2001

Eur J Anaesthesiol

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Section: Discussioncontrasting

confidence: 55%

What factors are associated with hyperlactatemia after cardiac surgery characterized by well-maintained oxygen delivery and a normal postoperative course? A retrospective study

Inoue¹,

Kuro²,

Furuya³

2001

Eur J Anaesthesiol

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“…Nociceptive surgical stimulations, volume variations due to acute blood losses or transfusions and administration of anesthetic agent can significantly influence this VO 2 -DO 2 relationship. Some studies evaluated the VO 2 -DO 2 relationship in major surgery [111][112][113] and showed a decreased capacity for tissue O 2 extraction which may have lead to tissue hypoxia [114]. These observations demonstrate the importance of adequately evaluating the DO 2 -VO 2 relationship in conjunction with the patient's metabolic demand, which is once again strongly affected by surgical conditions.…”

Section: Protocol For High Risk Surgerymentioning

confidence: 94%

Guiding Goal-Directed Therapy

Suehiro

Joosten

Alexander

2014

Curr Anesthesiol Rep

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Several studies have demonstrated that perioperative hemodynamic optimization (or ''goal directed therapy'') using minimally invasive hemodynamic monitoring technologies has the ability to improve postoperative patients' outcome with lower complication rates, shorter hospital lengths of stay, and lower cost of surgery. This specific concept of goal-directed therapy (GDT) uses perioperative cardiac output monitoring and manipulation of physiologic parameters (dynamic parameters of fluid responsiveness) to guide intravenous fluids and inotropic therapy with the goal of ensuring adequate tissue perfusion. Recently, the evidence related to the implementation of GDT strategies has been considered strong enough to allow for the creation of national recommendations in the UK, in France, and by the European Society of Anaesthesiology. The aims of the programs are to apply best practices to high-risk surgical patients and requires the participation of all clinicians involved in patients' care. Considering the potential clinical and economic benefits of GDT protocols and the positive recommendations from influential scientific societies, more and more hospitals around the world have become interested in implementing hemodynamic optimization in their departments. This review provides the information about the evolution of hemodynamic monitoring from invasive to the more recent noninvasive devices, and how these devices can be used in the operating rooms through well-defined algorithms of GDT.

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“…Waxman and coworkers [15] studied lactate levels during and after surgery. Although cardiac output and blood pressure did not 1 change intraoperatively, lactate levels increased.…”

mentioning

confidence: 99%