Sequential catalytic carbonylation reactions for sustainable synthesis of biologically relevant entities

Damas, Liliana; Rodrigues, Fábio M. S.; Gonzalez, Andreia C.S.; Carrilho, Rui M. B.; Gomez, Marta Piñeiro; Pereira, Mariette M.

doi:10.1016/j.jorganchem.2020.121417

Cited by 5 publications

(1 citation statement)

References 64 publications

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“…Carrilho and Pereira [ 109 ] developed an innovative methodology for the synthesis of highly functionalized formylcarboxamide derivatives with biological relevance, prepared by a sequential aminocarbonylation/hydroformylation approach. The first step involved a palladium‐catalyzed aminocarbonylation of iodoaromatic substrates with Pd(OAc) 2 as catalyst precursor using allylamine as nucleophile, DBU as base and Mo(CO) 6 as alternative CO source under microwave irradiation, yielding a set of N ‐heterocyclic‐ based allylcarboxamides (Scheme 53).…”

Section: Synthesis Of Fine Chemicals Using Comentioning

confidence: 99%

Carbon Monoxide as C1 Building Block in Fine Chemical Synthesis^†

Carrilho,

Calvete,

Mikle

et al. 2023

Chin. J. Chem.

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Carbon monoxide (CO) has become one of the most relevant and versatile renewable C1 building blocks for chemical synthesis, especially in the fine chemicals industry, due to the development of efficient and selective catalysts for its activation. In this review, we present a comprehensive critical analysis of the last 10 years literature on the use of CO as a renewable feedstock for fine chemicals production. The review is organized by type of catalytic reaction, namely alkene and alkyne carbonylation, hydroformylation, carbonylation of aryl halides, carbonylative cross‐coupling and C–H carbonylation. Notable examples of the synthesis of relevant building blocks and/or known pharmaceuticals are highlighted. Emphasis is placed on examples of utilizing CO as the C1 building block in one or more catalytic steps. The catalyst used and the reaction conditions are consistently presented throughout all of the examples.This article is protected by copyright. All rights reserved.

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Section: Synthesis Of Fine Chemicals Using Comentioning

confidence: 99%

Carbon Monoxide as C1 Building Block in Fine Chemical Synthesis^†

Carrilho,

Calvete,

Mikle

et al. 2023

Chin. J. Chem.

Self Cite

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Hydroformylation Catalysts for the Synthesis of Fine Chemicals

Pereira,

Carrilho,

Rodrigues

et al. 2024

Catalysis for a Sustainable Environment

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Transition Metal‐Catalyzed Transformations of Chalcones

Santos,

Silva

2024

The Chemical Record

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Chalcones are a class of naturally occurring flavonoid compounds associated to a variety of biological and pharmacological properties. Several reviews have been published describing the synthesis and biological properties of a vast array of analogues. However, overviews on the reactivity of chalcones has only been explored in a few accounts. To fill this gap, a systematic survey on the most recent developments in the transition metal‐catalyzed transformation of chalcones was performed. The chemistry of copper, palladium, zinc, iron, manganese, nickel, ruthenium, cobalt, rhodium, iridium, silver, indium, gold, titanium, platinum, among others, as versatile catalysts will be highlighted, covering the literature from year 2000 to 2023, in more than 380 publications.

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Sequential catalytic carbonylation reactions for sustainable synthesis of biologically relevant entities

Cited by 5 publications

References 64 publications

Carbon Monoxide as C1 Building Block in Fine Chemical Synthesis^†

Carbon Monoxide as C1 Building Block in Fine Chemical Synthesis^†

Hydroformylation Catalysts for the Synthesis of Fine Chemicals

Transition Metal‐Catalyzed Transformations of Chalcones

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Sequential catalytic carbonylation reactions for sustainable synthesis of biologically relevant entities

Cited by 5 publications

References 64 publications

Carbon Monoxide as C1 Building Block in Fine Chemical Synthesis†

Carbon Monoxide as C1 Building Block in Fine Chemical Synthesis†

Hydroformylation Catalysts for the Synthesis of Fine Chemicals

Transition Metal‐Catalyzed Transformations of Chalcones

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Product

Resources

About

Carbon Monoxide as C1 Building Block in Fine Chemical Synthesis^†

Carbon Monoxide as C1 Building Block in Fine Chemical Synthesis^†