Sequential bone healing of immediately loaded mini-implants: histomorphometric and fluorescence analysis

Micro-CT and histologic analyses of bone surrounding immediately loaded miniscrew implants: Comparing compression and tension loading

“…Serra et al 16) studied sequential bone healing of immediately loaded miniscrew implants and reported that there was no significant difference in BIC values between the compression and tension regions, although the values increased with healing time. Similarly, the mean BIC values in cortical and trabecular bone in the tension and compression regions in the present study were similar, suggesting that immediate loading of miniscrew implants did not affect osseointegration.…”

“…The implant images were quantitatively analyzed using computerassisted image-analysis software (Adobe Photoshop CS2, Adobe Systems, San Jose, California, USA) to calculate the percentage of bone-to-implant contact (BIC) on the compression and tension regions for cortical and trabecular bone (Fig. 6) [15][16][17] . For example, BIC values in the compression region for cortical bone = (the length of the bone and implant contact area in the compression region at the cortical bone) / (the length of the implant interface in the compression region at the cortical bone).…”

“…A variety of factors that may affect the primary stability and success rate of miniscrew implants, such as implant dimension 3,7) , implant length 8) , insertion orientation 9) , insertion torque 10) , and cortical bone thickness 11,12) , have been investigated. However, since immediate or early loading shortens the treatment period, with great clinical benefits for the orthodontist and patient, the effects of immediate loading have been histologically investigated for both self-tapping and self-drilling miniscrew implants [13][14][15][16][17] . A recent histologic investigation reported that immediate loading does not affect osseointegration of the miniscrew implant 15) .…”

The effects of different pilot-drilling methods on the mechanical stability of a mini-implant system at placement and removal: a preliminary study

“…7,11 One of the common findings in studies of orthodontic mini-screw systems that were stably used for an extended period of orthodontic application is that the surface of those mini-screw systems always showed some degree of osseointegration. 8,15,16 To date, no studies have reported any clinical situations where partially osseointegrated orthodontic mini-screws could not be removed by conventional unscrewing methods. However, the required motor-driven pilot drill to place the C-implant system has been a significant obstacle to an otherwise easy application of C-implant systems by orthodontists.…”

“…difficulty in removing the mini-screw when it is no longer needed for the orthodontic therapy), the advantages of partial osseointegration of orthodontic mini-screws have been wellstudied and documented. 15,16 In brief, the failure rate of mini-screw systems that purely rely on mechanical retention during orthodontic therapy is significantly higher than that for systems utilizing both osseointegration and mechanical retention. Furthermore, partial osseointegrated mini-screws have higher capability to withstand high levels of orthodontic force and rotational moments.…”