Sequential Acquisition of Human Papillomavirus Infection at Genital and Anal Sites, Liuzhou, China

Wei, Feixue; Su, Yingying; Cui, Xuelian; Yu, Xiaoqi; Li, Yafei; Song, Qingxu; Yin, Kai; Huang, Shou-Jie; Li, Mingqiang; Zhang, Jun; Wu, Ting; Xia, Ningshao

doi:10.3201/eid2610.191646

Cited by 10 publications

(15 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The HITCH cohort study, which enrolled young women (18–24 years old) and their male partners of over 4 months, indicated that HPV16/18 did not have particularly high transmission rates relative to other HPV types 30 . In the present study, only genital HPV 11 was significantly more common in those who practiced anal sex, which is interesting since this HPV type can cause anogenital lesions, and the risk for anal HPV infection in individuals with previous genital HPV seems to be higher than in individuals without an infection 31 .…”

Section: Discussionsupporting

confidence: 50%

Sexual practices and HPV infection in unvaccinated young adults

Pauli

Kops²,

Bessel³

et al. 2022

Sci Rep

View full text Add to dashboard Cite

The present study aimed to evaluate the association of genital and oral HPV infection among different sexual practices in both sexes. In total, 6388 unvaccinated men and women aged 16–25 years from all state capitals of Brazil were enrolled in through primary care services between September 2016 and November 2017. Genital and oral HPV genotyping was performed using the Roche Linear Array. Poisson regression analysis with robust variance was conducted to examine factors associated with overall HPV infection. A higher prevalence of genital HPV was found in women who practiced oral sex (57.85%) and in men who practiced all types of sex (65.87%). However, having more sexual partners and being younger were more important than the type of sex practiced. HPV 6 (7.1%) and 16 (10.5%) were significantly more prevalent in women who practiced oral sex, while HPV 6 (23.96%) and 11 (21.49%) were more prevalent in men who practiced anal sex. The type of sex was not associated with oral HPV prevalence. Genital and oral HPV infection were not associated by different sexual practices in the studied population.

show abstract

Section: Discussionsupporting

confidence: 50%

Sexual practices and HPV infection in unvaccinated young adults

Pauli

Kops²,

Bessel³

et al. 2022

Sci Rep

View full text Add to dashboard Cite

show abstract

“…This suggests either the same source of infection (ie, sexual partner), or autoinoculation between the genital and anal site. The theory of autoinoculation is supported by a recent study on sequential type-specific HPV infection, which found increased risk for sequential HPV infection at the anal site among participants who were positive for the same genotype at the genital site compared with those who were negative at the genital site, both for women and men 18. All men in this study were heterosexual men, making it hard to draw conclusions for MSM.…”

Section: Introductionmentioning

confidence: 73%

Type-specific concurrent anogenital HPV detection among young women and MSM attending Dutch sexual health clinics

et al. 2022

View full text Add to dashboard Cite

ObjectivesThis study aimed to investigate type-specific concurrent anogenital human papillomavirus (HPV) detection and examine associations with concurrent detection.MethodsData from a Dutch repeated cross-sectional study among young sexual health clinic visitors (Papillomavirus Surveillance among STI clinic Youngsters in the Netherlands) between 2009 and 2019 were used. Cohen’s kappa was used to assess the degree of type-specific concordance of HPV detection between anal and genital sites for 25 HPV genotypes for women and men who have sex with men (MSM) separately. Associations with type-specific concurrent HPV were identified. Receptive anal intercourse (RAI) was forced into the model to investigate its influence.ResultsAmong women (n=1492), type-specific concurrent anogenital detection was common; kappa was above 0.4 for 20 genotypes. Among MSM (n=614), kappa was <0.4 for all genotypes. The only significant association with type-specific concurrent anogenital detection among women was genital chlamydia (adjusted OR 1.5, 95% CI 1.1 to 2.2). RAI was not associated.ConclusionsType-specific concurrent anogenital HPV detection was common among young women, and uncommon among MSM. For women, concurrent HPV detection was associated with genital chlamydia. Our results are suggestive of autoinoculation of HPV among women.

show abstract

“…To our knowledge, these data provide the most robust evidence to date on the prevalence of HPV infection in men without established risk factors, highlighting background transmission in the absence of anal sexual intercourse (as observed in women). 41 This is an important concept, given that, because of population size, HIV-negative MSW still contribute a substantial proportion of anal cancer burden in men at a population level, 42 despite having a low risk at the individual level. HPV vaccination is the only, albeit longterm, solution to anal cancer prevention in HIV-negative MSW.…”

Section: Cytology Onlymentioning

confidence: 99%

Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies

et al. 2021

Self Cite

View full text Add to dashboard Cite

Background Robust age-specific estimates of anal human papillomavirus (HPV) and high-grade squamous intraepithelial lesions (HSIL) in men can inform anal cancer prevention efforts. We aimed to evaluate the age-specific prevalence of anal HPV, HSIL, and their combination, in men, stratified by HIV status and sexuality. MethodsWe did a systematic review for studies on anal HPV infection in men and a pooled analysis of individuallevel data from eligible studies across four groups: HIV-positive men who have sex with men (MSM), HIV-negative MSM, HIV-positive men who have sex with women (MSW), and HIV-negative MSW. Studies were required to inform on type-specific HPV infection (at least HPV16), detected by use of a PCR-based test from anal swabs, HIV status, sexuality (MSM, including those who have sex with men only or also with women, or MSW), and age. Authors of eligible studies with a sample size of 200 participants or more were invited to share deidentified individual-level data on the above four variables. Authors of studies including 40 or more HIV-positive MSW or 40 or more men from Africa (irrespective of HIV status and sexuality) were also invited to share these data. Pooled estimates of anal high-risk HPV (HR-HPV, including HPV16,

show abstract

Sequential Acquisition of Human Papillomavirus Infection at Genital and Anal Sites, Liuzhou, China

Cited by 10 publications

References 22 publications

Sexual practices and HPV infection in unvaccinated young adults

Sexual practices and HPV infection in unvaccinated young adults

Type-specific concurrent anogenital HPV detection among young women and MSM attending Dutch sexual health clinics

Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies

Contact Info

Product

Resources

About