Sequence signatures within the genome of SARS-CoV-2 can be used to predict host source
Josip Rudar,
Peter Kruczkiewicz,
Oksana Vernygora
et al.
Abstract:We conducted an
in silico
analysis to better understand the potential factors impacting host adaptation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in white-tailed deer, humans, and mink due to the strong evidence of sustained transmission within these hosts. Classification models trained on single nucleotide and amino acid differences between samples effectively identified white-tailed deer-, human-, and mink-derived SARS-CoV-2. For example, the balanced accurac… Show more
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