“…Of the patients 9 were homozygous for the most frequent disease-causing CFTR mutation ∆F508, 3 patients were ∆F508 compound heterozygotes and 1 patient carried the two exon 11 mutations G551D and R553X on her CF chromosomes (Table 1) [6,48]. The group covered the whole spectrum of mild (forced vital capacity (FVC) >80% predicted, patients 2, 6,8,9,10,13), moderate (FVC 60 -80% predicted, patients 1, 5, 12) and severe pulmonary disease (FVC <60% predicted, patients 3, 4, 7, 11) [36,48]. On the day of sampling all patients were in a clinically stable condition with no signs of pulmonary exacerbation.…”