Abstract:Sigma 1 Receptor is a subtype of opioid receptor that participates in membrane remodeling and cellular differentiation in the
nervous system. Sigma1 Receptor protein with amino acid length ranging from 229 is widely distributed in the liver and
moderately in the intestine, kidney, white pulp of the spleen, adrenal gland, brain, placenta and the lung. In this study, the three
dimensional structure for sigma 1 receptor protein has been developed by in- silico analysis based on evolutionary trace analysis of
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