Sequence analysis of SARS-CoV-2 Delta variant isolated from Makassar, South Sulawesi, Indonesia

Massi, Maurizio; Sjahril, Rizalinda; Halik, Handayani; Soraya, Gita Vita; Hidayah, Najdah; Pratama, Muhammad Yogi; Handayani, Irda; Gazali, Faris Muhammad; Hakim, Mohamad S.; Wibawa, Tri

doi:10.1016/j.heliyon.2023.e13382

Cited by 3 publications

(1 citation statement)

References 44 publications

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“…A total of 152 studies involving 41,409 patients from at least 23 countries have reported 26 different clinical manifestations of COVID-19 [1], [2]. Identification of all clinical manifestations of this disease is essential for early diagnosis and implementation of treatment measures [3].…”

Section: Introductionmentioning

confidence: 99%

Relationship Between Pulmonary Vascular Dilatation and Clinical Symptoms on Chest Computed Tomography in Patients with Confirmed COVID-19

Asriyani

Latief

Zainuddin

et al. 2023

Open Access Maced J Med Sci

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Introduction: Chest computed tomography (CT) is important in establishing a diagnosis, including detecting pulmonary vascular dilatation as a radiological feature of COVID-19, and consequently in providing comprehensive treatment. This study aimed to analyze the relationship between pulmonary vascular dilatation and clinical symptoms on chest CT in patients with confirmed COVID-19. Methods: This retrospective cross-sectional study was conducted at the Radiology Department of Dr. Wahidin Sudirohusodo Hospital and Hasanuddin University Hospital, Makassar, Indonesia, from July to September 2021 in a total of 231 patients with confirmed COVID-19. The chi-squared correlation test was used to analyze the data, with p-values of <0.05 considered significant. Results: Pulmonary vascular dilatation was observed in 31 (37.8%) of the 82 patients with confirmed COVID-19 with mild-to-moderate clinical symptoms and in 51 (69.8%) of the 73 patients with confirmed COVID-19 with severe-to-critical clinical symptoms. The incidence of pulmonary vascular dilatation increased in the patients with confirmed COVID-19 with severe-to-critical clinical symptoms. The chief complaints of most patients were cough, shortness of breath, and fever. In the patients with mild-to-moderate clinical symptoms, the most common chief complaint was cough (n=53; 64.63%), while in those with severe-to-critical clinical symptoms, the most common chief complaint was shortness of breath (n=60; 82.19%). Conclusions: Based on chest CT findings, pulmonary vascular dilatation is related to clinical symptoms in patients with confirmed COVID-19.

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Section: Introductionmentioning

confidence: 99%

Relationship Between Pulmonary Vascular Dilatation and Clinical Symptoms on Chest Computed Tomography in Patients with Confirmed COVID-19

Asriyani

Latief

Zainuddin

et al. 2023

Open Access Maced J Med Sci

View full text Add to dashboard Cite

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Sequence analysis of the Spike, RNA-dependent RNA polymerase, and protease genes reveals a distinct evolutionary pattern of SARS-CoV-2 variants circulating in Yogyakarta and Central Java provinces, Indonesia

Hakim,

Gunadi,

Rahayu

et al. 2024

Virus Genes

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The Compatibility of Chest CT Scan with RT-PCR in Suspected COVID-19 Patients

Asriyani

Alfonso

Muis

et al. 2023

Open Access Maced J Med Sci

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Background: Thoracic CT scan plays a role in detecting and assessing the progression of COVID-19. It can evaluate the response to the therapy given. In diagnosis, the CT scan of the chest may complement the limitations of RT-PCR. Several recent studies have discussed the importance of CT scans in COVID-19 patients with false-negative RT-PCR results. The sensitivity of chest CT scan in the diagnosis of COVID-19 is reportedly around 98%. This study aimed to determine the compatibility of CT scan of the thorax with RT-PCR in suspected COVID-19 patients. Materials and methods: This research was conducted in the Radiology Department of the Wahidin Sudirohusodo Hospital Makassar from April to December 2020 with 350 patients. The method used was a 2x2 table diagnostic test. Results: The study included 188 male patients (53.7%) and 162 female patients (46.2%). The most common age group was 46–65 years (35.4%). The most common types of lesions were GGO (163 cases), consolidation (128 cases), and fibrosis (124 cases), mostly found in the inferior lobe with a predominantly peripheral or subpleural distribution. The sensitivity of the CT scan to the PCR examination was 86%, and the specificity was 91%. Conclusions: Thoracic CT scan was a good modality in establishing the diagnosis of COVID-19. CT scan of the chest with abnormalities could confirm the diagnosis in 88% of cases based on RT-PCR examination. It excluded the diagnosis in 91% based on the RT-PCR examination. The accuracy of the thoracic CT scan was 88% with RT-PCR as the reference value.

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Sequence analysis of SARS-CoV-2 Delta variant isolated from Makassar, South Sulawesi, Indonesia

Cited by 3 publications

References 44 publications

Relationship Between Pulmonary Vascular Dilatation and Clinical Symptoms on Chest Computed Tomography in Patients with Confirmed COVID-19

Relationship Between Pulmonary Vascular Dilatation and Clinical Symptoms on Chest Computed Tomography in Patients with Confirmed COVID-19

Sequence analysis of the Spike, RNA-dependent RNA polymerase, and protease genes reveals a distinct evolutionary pattern of SARS-CoV-2 variants circulating in Yogyakarta and Central Java provinces, Indonesia

The Compatibility of Chest CT Scan with RT-PCR in Suspected COVID-19 Patients

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