Sequelae of Systemic Hypertension in Alcohol Abstainers, Light Drinkers, and Heavy Drinkers

The J-shape association of alcohol consumption on blood pressure levels, in elderly people from Mediterranean Islands (MEDIS epidemiological study)

“…[3][4][5] Additionally, the antioxidant effect of both alcohol and the associated non-alcoholic components of beverages, such as polyphenols, may contribute to diminish the risk of hypertension. 2 Taking into account that high blood pressure levels are common in the elderly, 11,12 and the previous reports, it could be suggested that moderate alcohol intake reduces the burden of hypertension in elder people, through decreasing peripheral resistance (i.e., vasodilator activity) and increasing compliance (i.e., maintaining the elasticity of arterial wall through prevention of atherosclerosis). Although important associations were assessed, the cross-sectional design of this study prohibits causal interpretations.…”

“…[1][2][3][4][5][6] Observational studies support that moderate alcohol consumption is associated with lower risk of CVD, whereas others reported that alcohol intake is not associated with an increase in coronary risk. 2 As the long-term effect of alcohol consumption on blood pressure, especially in elderly populations, has rarely been studied, we evaluated whether alcohol intake is associated with blood pressure, in a sample of elderly men and women living in Mediterranean islands (MEDIS study).…”

“…8 However, in another prospective study the authors reported that alcohol consumption has contrasting relations to CVD. 2 Regarding the shape of the dose-response relationship between alcohol intake and CVD risk, the results are inconsistent. Several studies have reported inverse relationship with no evidence of higher risk with heavier drinking and others have demonstrated a U-or J-shaped function.…”

Interação Medicamentosa Entre Fármacos Anti-Hipertensivos Em Usuários De Bebida Alcoólica

“…Sabe-se que a hipertensão arterial sistêmica é também considerada um importante fator de risco por não apresentar sintomatologia, em parte da população acometida, e por levar a eventos cardiovasculares fatais e não fatais, destacandose assim, o acidente vascular encefálico (AVE) e a doença isquêmica do coração (DIC) [3][4][5] .…”

“…Essa terapia é utilizada para prevenir doenças cardiovasculares e manter os níveis de pressão arterial controlados abaixo de 130x85mmHg [1][2][3][4][5][6][7] . Na regulação da pressão arterial além das medidas farmacológicas, também são recomendadas medidas primárias como redução do peso, controle do açúcar e alimentos gordurosos, exercício físico e diminuição do consumo de bebidas alcoólicas [1][2][3][4][5][6][7][8] . Apesar da eficácia medicamentosa ser comprovada, o comportamento do indivíduo com relação à mudança no estilo de vida também contribui significativamente para prevenir o desenvolvimento de HAS 1,5,9 .…”