Sequelae associated with cerebral candidiasis in two premature infants

presented with leg weakness and pain, followed in 2 to 6 days by loss of pain and temperature sensation, and finally complete myelopathy, with proprioceptive loss and urinary incontinence. One patient had brain involvement also, manifesting with delirium, spasticity, and arm weakness. Despite aggressive antifungal therapy, the patients died within 1 month of onset of symptoms. Postmortem findings showed multifocal meningeal exudates, cerebral and spinal hemorrhagic necrosis, and fungal abscess in the cord of one child, and aortic endarteritis, spinal necrosis and intramedullary hematoma in a second. A third, without postmortem, had shown CT and MRI evidence of a paravertebral mass with certebral osteomyelitis, and a positive biopsy culture for Aspergillus. Blood and CSF cultures were negative.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Sequelae associated with cerebral candidiasis in two premature infants

Abstract: This study reports on two premature infants who developed cerebral candidiasis and survived. Both were found to have significant handicaps on follow‐up.

Cited by 3 publications

References 10 publications

Central nervous system candidiasis in the high-risk neonate

Central nervous system candidiasis in the high-risk neonate

Candidiasis cerebral en un recién nacido

Cerebral Candidiasis Sequelae in Premature Infants

Contact Info

Product

Resources

About