Septins are involved in nuclear division, morphogenesis and pathogenicity in Fusarium graminearum

Chen, Ahai; Xie, Qiurong; Lin, Yunzhi; Xu, Huaijian; Shang, Wenjie; Zhang, Jun; Zhang, Dongmei; Zheng, Wenhui; Li, Guangpu; Wang, Zonghua

doi:10.1016/j.fgb.2016.07.005

Cited by 33 publications

(42 citation statements)

References 56 publications

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“…In filamentous ascomycetes, deletion of septin genes does not abolish septation but significantly reduces the number of septa in the hyphae (Berepiki & Read, 2013;Chen et al, 2016;Dagdas et al, 2012;Hernandez-Rodriguez et al, 2012;Lindsey et al, 2010a;Vargas-Muñiz et al, 2015). In Sac.…”

Section: Septins Control Regularity Of Septation and Sporulationmentioning

confidence: 99%

“…cerevisiae, Ash. gossypii and F. graminearum, septins are involved in ascospore formation (Chen et al, 2016;Fares et al, 1996;Heasley & McMurray, 2016;Meseroll et al, 2013). Similarly, in N. crassa, Asp.…”

Section: Septins Control Regularity Of Septation and Sporulationmentioning

confidence: 99%

“…nidulans, Asp. fumigatus and F. graminearum, septins play a critical role in the production of conidia (Berepiki & Read, 2013;Chen et al, 2016;Hernandez-Rodriguez et al, 2012;Lindsey et al, 2010a;Vargas-Muñiz et al, 2015). While disorganization of conidiophores occurs in all the A. nidulans core septin deletion strains, the conidiophores in Asp.…”

Section: Septins Control Regularity Of Septation and Sporulationmentioning

confidence: 99%

“…Also, in another plant pathogen, F. graminearum, the deletion of core septins caused reduction in pathogenicity (Chen et al, 2016). However, contribution of septins to virulence is not conserved among all plant pathogenic fungi.…”

Section: Septins Control Regularity Of Septation and Sporulationmentioning

confidence: 99%

“…In addition to septins regulating cell division, they have also been implicated in a myriad of cellular processes such as cytoskeleton organization, vesicle trafficking, morphogenesis and cell wall maintenance (Table 1) (Chen et al, 2016;Dagdas et al, 2012;Hernandez-Rodriguez et al, 2012;Kozubowski & Heitman, 2010;Li et al, 2012b;Lindsey et al, 2010a;Oh & Bi, 2011;Vargas-Muñiz et al, 2015). In light of more recent literature emerging in the field of fungal septins, here we review the divergent roles of septins in the model and pathogenic fungi, with emphasis on their assembly into higher order structures and their post-translation modification involving phosphorylation and dephosphorylation.…”

Section: Introductionmentioning

confidence: 99%

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Forging the ring: from fungal septins' divergent roles in morphology, septation and virulence to factors contributing to their assembly into higher order structures

2016

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Septins are a conserved family of GTP-binding proteins that are distributed across different lineages of the eukaryotes, with the exception of plants. Septins perform a myriad of functions in fungal cells, ranging from controlling morphogenetic events to contributing to host tissue invasion and virulence. One key attribute of the septins is their ability to assemble into heterooligomeric complexes that organizse into higher order structures. In addition to the established role of septins in the model budding yeast, Saccharomyces cerevisiae, their importance in other fungi recently emerges. While newer roles for septins are being uncovered in these fungi, the mechanism of how septins assemble into a complex and their regulation is only beginning to be comprehended. In this review, we summarize recent findings on the role of septins in different fungi and focus on how the septin complexes of different fungi are organized in vitro and in vivo. Furthermore, we discuss on how phosphorylation/dephosphorylation can serve as an important mechanism of septin complex assembly and regulation.

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Section: Septins Control Regularity Of Septation and Sporulationmentioning

confidence: 99%

Section: Septins Control Regularity Of Septation and Sporulationmentioning

confidence: 99%

Section: Septins Control Regularity Of Septation and Sporulationmentioning

confidence: 99%

Section: Septins Control Regularity Of Septation and Sporulationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Forging the ring: from fungal septins' divergent roles in morphology, septation and virulence to factors contributing to their assembly into higher order structures

2016

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The emerging role of septins in fungal pathogenesis

2023

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Fungal pathogens undergo specific morphogenetic transitions in order to breach the outer surfaces of plants and invade the underlying host tissue. The ability to change cell shape and switch between non‐polarised and polarised growth habits is therefore critical to the lifestyle of plant pathogens. Infection‐related development involves remodelling of the cytoskeleton, plasma membrane and cell wall at specific points during fungal pathogenesis. Septin GTPases are components of the cytoskeleton that play pivotal roles in actin remodelling, micron‐scale plasma membrane curvature sensing and cell polarity. Septin assemblages, such as rings, collars and gauzes, are known to have important roles in cell shape changes and are implicated in formation of specialised infection structures to enter plant cells. Here, we review and compare the reported functions of septins of plant pathogenic fungi, with a special focus on invasive growth. Finally, we discuss septins as potential targets for broad‐spectrum antifungal plant protection strategies.

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ESCRT-III accessory proteins regulate fungal development and plant infection in Fusarium graminearum

et al. 2019

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Septins are involved in nuclear division, morphogenesis and pathogenicity in Fusarium graminearum

Cited by 33 publications

References 56 publications

Forging the ring: from fungal septins' divergent roles in morphology, septation and virulence to factors contributing to their assembly into higher order structures

Forging the ring: from fungal septins' divergent roles in morphology, septation and virulence to factors contributing to their assembly into higher order structures

The emerging role of septins in fungal pathogenesis

ESCRT-III accessory proteins regulate fungal development and plant infection in Fusarium graminearum

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