Septicemic Adrenal Hemorrhage

Margaretten, William; Nakai, Hisayo; Landing, Benjamin H.

doi:10.1001/archpedi.1963.02080040348004

Cited by 20 publications

(18 citation statements)

References 8 publications

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“…focus remains unknown [5,7], In our cases bacterial examination of abscess material revealed E. coli (case 1) and S. aureus (case 2), but Streptococcus, Bacteroides, Echovirus and herpes simplex could also be isolated [1,2,5,7,15,16].…”

mentioning

confidence: 56%

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Neonatal Adrenal Abscesses

Steffens

Zaubitzer²,

Kirsch³

et al. 1997

Eur Urol

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mentioning

confidence: 56%

“…However, some infants are totally asymptomatic [10,15]. Bacterial seeding was sometimes correlated with maternal infections, but in most cases the the abscess and involvement of adjacent organs [1,2,4,16].…”

mentioning

confidence: 99%

Neonatal Adrenal Abscesses

Steffens

Zaubitzer²,

Kirsch³

et al. 1997

Eur Urol

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“…Meningococcaemia is the most common culprit,10 however, other pathogens have been found to precipitate haemorrhagic infarction (including Pseudomonas aeruginosa ,11 Streptococcus pneumoniae , Neisseria gonorrhoeae , Escherichia coli , Haemophilus influenzae , Staphylococcus aureus ) 1. The typical clinical presentation closely correlates with how this patient presented (figure 5).…”

Section: Discussionmentioning

confidence: 99%

Bilateral adrenal haemorrhagic infarction in a patient with antiphospholipid syndrome

Clark

2014

BMJ Case Reports

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SUMMARYA 68-year-old woman with antiphospholipid syndrome presented with a 3-day history of bilateral loin pain, vomiting, fever and confusion. On examination she was febrile, hypotensive and tachycardic. Investigations revealed raised inflammatory markers, renal impairment and hyponatraemia. Abdominal ultrasound revealed two well-defined heterogeneous areas bilaterally in the region of the adrenal glands. This prompted serum cortisol measurement and a CT of the abdomen. Cortisol was low in the context of sepsis at 48 nmol/L, and CT confirmed bilateral heterogeneous adrenal pathology. The patient was managed for septic shock and adrenal insufficiency. She was recognised to have several risk factors for haemorrhagic infarction of the adrenals: antiphospholipid syndrome, sepsis, postoperative state and anticoagulant therapy. She was discharged well on glucocorticoid and mineralocorticoid therapy and a repeat CT at 4 weeks confirmed the diagnosis of bilateral adrenal infarct and haemorrhage. BACKGROUND

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“…In children, bilateral hemorrhage is commonly associated with pseudomonas or meningococcal septicemia (Waterhouse-Friderichsen syndrome) [5,6].…”

Section: Primary Adrenal Insufficiencymentioning

confidence: 99%

Adrenal insuficiency: Diagnosis and management

Munver

Volfson²

2006

Curr Urol Rep

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Adrenal insufficiency is a disorder characterized by hypoactive adrenal glands resulting in insufficient production of the hormones cortisol and aldosterone by the adrenal cortex. This disorder may develop as a primary failure of the adrenal cortex or be secondary to an abnormality of the hypothalamic-pituitary axis. Patients with adrenal insufficiency often are asymptomatic or they may present with fatigue, muscle weakness, weight loss, low blood pressure, and sometimes darkening of the skin. The presentation of adrenal insufficiency varies dramatically and poses a major diagnostic dilemma. This review focuses on the diagnosis and treatment of primary and secondary adrenal insufficiency.

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Septicemic Adrenal Hemorrhage

Cited by 20 publications

References 8 publications

Neonatal Adrenal Abscesses

Neonatal Adrenal Abscesses

Bilateral adrenal haemorrhagic infarction in a patient with antiphospholipid syndrome

Adrenal insuficiency: Diagnosis and management

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