Septic pulmonary embolisms as a cause of acute respiratory distress syndrome

Prnjavorac, Besim; Sejdinović, Rifat; Jusufovic, Edin; Mehic, Jusuf; Bedak, Omer; Fejzic, Jasmin; Irejiz, Nedzada; Malenica, Maja; Bego, Tamer; Dujić, Tanja; Čaušević, Adlija; L, Hantalasević; Mehmedović, Amila; Krajina, Katarina; Mujaric, Ekrema; Šaranović, Lejla

doi:10.1183/13993003.congress-2016.pa2443

Cited by 2 publications

(4 citation statements)

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“…Indeed, the severity of peripheral occlusive arterial disease correlates with the levels of both fibrinogen and its turnover measure D-dimer. 2 In severe COVID-19 infection, elevation of D-dimer and sepsisinduced coagulopathy (SIC) predicts a poor prognosis. The incidence of venous thromboembolism in patients with severe COVID-19 pneumonia is 25% (!).…”

Section: Covid-19 and Sic (!)mentioning

confidence: 99%

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The role of vascular surgeons in the treatment of COVID-19-associated pulmonary embolism

Patelis

Bisdas

Tsiachris

et al. 2020

Journal of Vascular Surgery

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Section: Covid-19 and Sic (!)mentioning

confidence: 99%

“…It is already described that disseminated intravascular coagulation can occur in patients with severe COVID-19 leading to SPE. [1][2][3] COVID-19-related SPE is already described as a lethal complication and a negative prognostic factor. 4 Published data on COVID-19-related SPE remains limited to a small number of case reports.…”

mentioning

confidence: 99%

The role of vascular surgeons in the treatment of COVID-19-associated pulmonary embolism

Patelis

Bisdas

Tsiachris

et al. 2020

Journal of Vascular Surgery

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“…Septicemia due to iliac vein thrombophlebitis is a direct source of bacterial seeding from the abdomen into the right side of the heart. Venous embolic phenomena from iliac veins has an insidious onset of events which could cause severe acute respiratory distress syndrome [8]. The pathogenesis of acute respiratory distress syndrome in the setting of septic emboli relates to systemic in lammatory reaction with localized alveolar damage and subsequent impairment of ventilation [8].…”

Section: Introductionmentioning

confidence: 99%

“…Venous embolic phenomena from iliac veins has an insidious onset of events which could cause severe acute respiratory distress syndrome [8]. The pathogenesis of acute respiratory distress syndrome in the setting of septic emboli relates to systemic in lammatory reaction with localized alveolar damage and subsequent impairment of ventilation [8]. This acute in lammatory response to a bacterial organism makes prompt initiation of effective antibiotic therapy a critical role in management.…”

Section: Introductionmentioning

confidence: 99%

Embolic Septic Emboli with MRSA: A different source

Latorre¹,

Agosto²,

Hernandez³

et al. 2019

J Clin Intensive Care Med

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Septic Iliac vein thrombophlebitis with associated psoas abscess is a rare and severe entity, which diagnosis is challenging when no risk factor is clearly present. We are presenting a case of severe septic cavitary pulmonary emboli complicated with Acute Respiratory Distress Syndrome (ARDS) that evolved rapidly to respiratory distress and multi organ failure. A 61-year-old Hispanic male, had multiple emergency department visits due to back pain, being most of them intramuscular pain medications and steroids. In the history, he had back pain that worsened accompanied by poor mobility, generalized malaise, fever and chills. Computed tomography (CT) scan showed a paravertebral psoas abscess with L5-S1 diskitis/spondylitis infl ammatory changes, which was then later evidenced by a gallium study. Further imaging studies were done, showed bilateral cavitary lung lesions, consistent with septic emboli. Subsequent blood cultures were positive for Methicillin Resistant Staphylococcus Aureus (MRSA), for which a successful combined therapeutic regimen was used. Transthoracic and transesophageal echocardiogram were not suggestive of endocarditis. Staphylococcus aureus (SA) bacteremia is one of the most common serious bacterial infections with a high risk of metastatic complications, which makes this pathogen a unique one. The combination of factors iliac vein thrombophlebitis, psoas muscle abscess, diskitis/spondylitis with ARDS makes cavitary pulmonary disease a challenging perspective. After a 6-week antimicrobial treatment, full anticoagulation, his clinical condition and image fi ndings improved, and he was recently admitted for physical rehabilitation. Major vessels thrombophlebitis should always be considered, when primary source of septic pulmonary emboli is not clear. This case illustrates the complexity of illness and complications that may arise from a source of infection as the one in this patient. Further therapeutic strategies were tailored accordingly.

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Septic pulmonary embolisms as a cause of acute respiratory distress syndrome

Cited by 2 publications

References 0 publications

The role of vascular surgeons in the treatment of COVID-19-associated pulmonary embolism

The role of vascular surgeons in the treatment of COVID-19-associated pulmonary embolism

Embolic Septic Emboli with MRSA: A different source

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