Septic arthritis incidence and risk factors: a 5-year cross-sectional study

Figueiredo, Inês; Alves, Rita Vieira; Castro, Sara Guerreiro; Antunes, Ana; Gruner, Heidi; Panarra, António

doi:10.1080/23744235.2019.1633471

Cited by 4 publications

(4 citation statements)

References 8 publications

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“…The prevalence and incidence increased with age, mainly among those ≥ 60 years of age. The age group of septic arthritis in Thais was similar to the age group of septic arthritis in the Portuguese population (median age 67 years), 10 the New Zealand population (mean age 60 years), 11 and the Maltese population (median age 66 years). 12 However, the age group was slightly higher than in a previous study of the Thai population.…”

Section: Discussionsupporting

confidence: 57%

“…Septic arthritis in Thais was comparable between males and females, while previous studies reported a male predominance with a male-to-female ratio around 2:1 to 1.5:1. 10,12,13,17,19 The more significant number of females in the Thai population could explain the finding 5 as well as the longer life expectancy of Thai females over Thai males. 20 According to our results, wherein incidence increased with age, it is possible that elderly females might have an increased risk of septic arthritis with age.…”

Section: Discussionmentioning

confidence: 95%

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Incidence and Prevalence of Septic Arthritis in Thailand: A Database from the Ministry of Public Health

Foocharoen,

Onchan,

Pongkulkiat

et al. 2023

OARRR

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Background: A better understanding of the epidemiological profile of septic arthritis or pyogenic arthritis in Thais could improve care and provide information for better infectious control. We aimed to determine the incidence and prevalence of septic arthritis in Thailand between 2017 and 2020. Methods: A descriptive epidemiological study was performed using demographic data from patients over 18 years of age having a primary diagnosis of M00 pyogenic arthritis between 2017 and 2020. Data were sourced from the Information and Communication Technology Center, Ministry of Public Health database. The incidence and prevalence of septic arthritis were calculated, and their respective 95% confidence interval (CI).

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Section: Discussionsupporting

confidence: 57%

Section: Discussionmentioning

confidence: 95%

Incidence and Prevalence of Septic Arthritis in Thailand: A Database from the Ministry of Public Health

Foocharoen,

Onchan,

Pongkulkiat

et al. 2023

OARRR

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“…Most of the published reports are from retrospective cohort studies such as this one. Although there are retrospective studies on the epidemiology and clinical presentation of AS in Portugal, 13,14 to the best of our knowledge this is the first Portuguese study that evaluates the adequacy of the empirical antibiotic regimens with the microbiological isolates and the antimicrobial susceptibility patterns.…”

Section: Discussionmentioning

confidence: 99%

“…It is considered a rare agent, being mostly associated with older patients, joint injection site infections, prosthesis infections and immunocompromised host infections. 2,13,18 Gram-negative bacteria (GNB) are traditionally considered an uncommon cause of SA in native joints. 1 They are much more commonly found in nosocomial or health care-related infections such as prosthetic joint infection (PJI).…”

Section: Discussionmentioning

confidence: 99%

Adult Native Joint Septic Arthritis: A Nine-Year Retrospective Analysis in a Portuguese University Hospital

et al. 2021

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Introduction: Septic arthritis of a native joint represents a medical emergency. Drainage and effective antibiotic treatment are critical to avoid joint destruction and long-term impairment. The aim of this study was to evaluate epidemiological and clinical characteristics of patients with the diagnosis of septic arthritis to help establish local guidelines for empirical antibiotic treatment.Material and Methods: Retrospective analysis of adult patients admitted at Centro Hospitalar Universitário do Porto from 2009 to 2017 with suspected native joint septic arthritis. Relevant demographics, microbiology findings and respective antibiotic susceptibilities were analysed.Results: Ninety-seven patients, predominantly males (59.8%) with a median age of 61 years old were included. The most commonly reported comorbidity associated with septic arthritis was diabetes mellitus (20.6%). The knee was the most commonly affected joint (71.1%). Arthrocentesis was performed in all patients, but only 50.5% had positive microbial growth in the synovial fluid. Staphylococcus aureus was the most frequently identified microorganism, 86% of which were methicillin susceptible. Gram-negative bacteria were the causative agent in 15% of cases. A wide range of empirical antibiotic regimens were prescribed with a combination of vancomycin/carbapenem being the most common (30.9%). Analysis of antibiotic susceptibility profiles revealed that amoxicillin/clavulanate would have been appropriate as the initial regimen in 89% of cases.Discussion: The main causative pathogen was Staphylococcus aureus, with methicillin resistant Staphylococcus aureus remaining rare. The proportion of Gram-negative bacteria implies that these agents should be covered by empirical treatment, although no case of Pseudomonas infection has been identified. Therefore, antipseudomonal coverage is not necessary in empirical regimens.Conclusion: Routine coverage of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa is not warranted but must be considered when specific risk factors are found. Amoxicillin/clavulanate can provide adequate antibiotic coverage as an empirical treatment for adult native joint septic arthritis. Its use may allow a reduction in use of broader spectrum antibiotics.

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