Septic Arthritis due to Absidia corymbifera in a Patient with HIV-1 Infection

Parra-Ruiz, Jorge; Peña-Monje, Alejandro; Tomás-Jiménez, Cristina; Antelo-Lorenzo, R.; Escobar-Lara, T.; Hernández-Quero, José

doi:10.1007/s15010-007-6297-3

Cited by 13 publications

(6 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…; isolated panendophthalmitis; knee septic arthritis and isolated spleen abscess). 16,21,22 Other opportunistic diseases associated with mucormycosis infection…”

Section: Clinical Categoriesmentioning

confidence: 99%

The burden of mucormycosis in HIV-infected patients: A systematic review

Moreira

Varon

Galhardo

et al. 2016

Journal of Infection

View full text Add to dashboard Cite

show abstract

“…; isolated panendophthalmitis; knee septic arthritis and isolated spleen abscess). 16,21,22 Other opportunistic diseases associated with mucormycosis infection…”

Section: Clinical Categoriesmentioning

confidence: 99%

The burden of mucormycosis in HIV-infected patients: A systematic review

Moreira

Varon

Galhardo

et al. 2016

Journal of Infection

View full text Add to dashboard Cite

show abstract

“…There is one case of Absidia corymbifera causing septic arthritis in a patient with AIDS. The exact mechanism of inoculation was not determined (Parra-Ruiz et al , 2008). There was also a case of Cunninghamella bertholletiae articular mucormycosis, also in a patient with AIDS.…”

Section: Discussionmentioning

confidence: 99%

“…Mucoraceous moulds rarely cause septic arthritis, with only a few case reports described (Mostaza et al , 1989; Parra-Ruiz et al , 2008). In this report, we present a patient with multiple myeloma who presented with persistent septic arthritis of the left knee, who ultimately was found to have A. trapeziformis growing from his synovial cultures.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic difficulty identifying Apophysomyces trapeziformis septic arthritis in a patient with multiple myeloma

et al. 2016

View full text Add to dashboard Cite

Introduction:Mucormycosis is a rare fungal infection, but can cause substantial morbidity and mortality in both immunocompromised and immunocompetent patients. Apophysomyces is a mucormycetes species ubiquitous in nature, particularly in soil, decaying wood and other organic matter. Apophysomyces is known to cause cutaneous fungal infections, particularly after penetrating trauma. Septic arthritis is a rare clinical manifestation.Case presentation:We describe a case of Apophysomyces trapeziformis causing septic arthritis of the knee of a patient with multiple myeloma. He was treated multiple times for bacterial septic arthritis with minimal improvement. Surgical tissue specimens finally grew mucoraceous mould, and DNA sequencing and morphological assessment of spores identified the mould as A. trapeziformis. The patient was treated with amphotericin B and posaconazole, but ultimately required an above-the-knee amputation for definitive treatment.Conclusion:This case illustrates the need to evaluate for fungal infection in a persistent septic arthritis that is culture negative and refractory to empiric antibiotics, particularly in an immunocompromised individual. It also shows the importance of a thorough social history and adequate tissue specimens for culture.

show abstract

“…11,12,41 Fungal Arthritis and Osteomyelitis The reported causative organisms of fungal arthritis and osteomyelitis include Candida albicans, Histoplasma capsulatum, Cryptococcus neoformans, Sporothrix schenckii, Penicillium marneffei, Absidia corymbifera, and Mucor spp. [7][8][9]13,42,43 C. albicans is the most common cause of fungal arthritis among IVDUs. Bone and joint infections caused by fungal infection usually occur in the disseminated disease setting.…”

Section: Mycobacterial Arthritis and Osteomyelitismentioning

confidence: 99%

Musculoskeletal Infection in Acquired Immunodeficiency Syndrome

Pattamapaspong

Louthrenoo

2011

Semin Musculoskelet Radiol

View full text Add to dashboard Cite

Musculoskeletal infection is one of the common manifestations of patients infected with human immunodeficiency virus and acquired immunodeficiency syndrome. With immune deficiency, patients are susceptible to a variety of nonopportunistic and opportunistic infections that can result in significant morbidity and mortality. Infection can involve any anatomical compartments resulting in infectious arthritis, osteomyelitis, pyomyositis, and soft tissue and skin infection. Imaging plays an important role in the early diagnosis and treatment planning for these patients. This article reviews the clinical manifestations of musculoskeletal infection together with reported causative organisms. We discuss the role of imaging and present radiological examples.

show abstract

Septic Arthritis due to Absidia corymbifera in a Patient with HIV-1 Infection

Abstract: We report the first case described of septic arthritis caused by Absidia corymbifera in the setting of cellular immune deficiency associated with HIV-1 infection. Isolation of this organism from sterile fluids as synovial fluid should be regarded as pathogenic.

Cited by 13 publications

References 15 publications

The burden of mucormycosis in HIV-infected patients: A systematic review

The burden of mucormycosis in HIV-infected patients: A systematic review

Diagnostic difficulty identifying Apophysomyces trapeziformis septic arthritis in a patient with multiple myeloma

Musculoskeletal Infection in Acquired Immunodeficiency Syndrome

Contact Info

Product

Resources

About