Introduction: Genital microbiome of woman is still a puzzle to this day. It consists of a large number of diff erent bacterial species and phenotypes that make up the normal genital fl ora, while in the cases of its change there is a predominance of certain, especially anaerobic species, which is the case with bacterial vaginosis. These types are mostly rare causing invasive infections, but under certain conditions can lead to severe infections, such as multiple parts of the genital tract, and to an unwanted outcome in the pregnancy. Case report: This paper presents an extremely rare case of transient bacteremia caused by Atopobium vaginae type in a patient following a cesarean section where empirical therapy gave a positive eff ect and the patient recovered and released home with healthy newborn. Conclusions: During the clinical work it is important to be aware of the diff erent anaerobic species present in the genital tract of women microbiome like Atopobium vaginae and should adjust the empirical therapy, which was the case here.