Sepse Brasil: estudo epidemiológico da sepse em Unidades de Terapia Intensiva brasileiras

Júnior, João Andrade L. Sales; David, Cid Marcos; Hatum, R; Souza, Patterson P. de; Japiassú, André Miguel; Pinheiro, Cleovaldo T. S.; Friedman, Gilberto; Silva, Odin Barbosa da; Dias, Mariza DAgostino; Koterba, Edwin; Dias, Fernando Suparregui; Piras, Cláudio; Luiz, Ronir Raggio

doi:10.1590/s0103-507x2006000100003

Cited by 91 publications

(86 citation statements)

References 35 publications

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“…Several studies show a variable average stay from 4.09 to 28.8 days, 13,15,19,24,[28][29][30] which places us in a comfortable position with the average of 8.09 days. We can assume that the possible causes of these large variations in mean hospital stay are related to the age and preexisting comorbidities in individuals of the studies in question, including ours.…”

Section: Discussionmentioning

confidence: 99%

Epidemiological profile of ICU patients at Faculdade de Medicina de Marília

El-Fakhouri

Carrasco

Araújo

et al. 2016

Rev. Assoc. Med. Bras.

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Objective: To characterize the epidemiological profile of the hospitalized population in the ICU of Hospital das Clínicas de Marília (Famema). Method: A retrospective, descriptive and quantitative study. Data regarding patients admitted to the ICU Famema was obtained from the Technical Information Center (Núcleo Técnico de Informações, NTI, Famema). For data analysis, we used the distribution of absolute and relative frequencies with simple statistical treatment. Results: 2,022 ICU admissions were recorded from June 2010 to July 2012 with 1,936 being coded according to the ICD-10. The epidemiological profile comprised mostly males (57.91%), predominantly seniors ≥ 60 years (48.89%), at an average age of 56.64 years (±19.18), with limited formal education (63.3% complete primary school), mostly white (77.10%), Catholic (75.12%), from the city of Marília, state of São Paulo, Brazil (53.81%). The average occupancy rate was 94.42%. The predominant cause of morbidity was diseases of the circulatory system with 494 admissions (25.5%), followed by traumas and external causes with 446 admissions (23.03%) and neoplasms with 213 admissions (11.00%). The average stay was 8.09 days (±10.73). The longest average stay was due to skin and subcutaneous tissue diseases, with average stay of 12.77 days (±17.07). There were 471 deaths (24.32%), mainly caused by diseases of the circulatory system (30.99%). The age group with the highest mortality was the range from 70 to 79 years with 102 deaths (21.65%). Conclusion:The ICU Famema presents an epidemiological profile similar to other intensive care units in Brazil and worldwide, despite the few studies available in the literature. Thus, we feel in tune with the treatment of critical care patients.

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Section: Discussionmentioning

confidence: 99%

Epidemiological profile of ICU patients at Faculdade de Medicina de Marília

El-Fakhouri

Carrasco

Araújo

et al. 2016

Rev. Assoc. Med. Bras.

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“…The Brazilian Sepsis Epidemiological Study (Bases Study), conducted in fi ve ICU, found mortality rates of 11%, 33.9%, 46.9% and 52.2% in patients with SIRS, sepsis, severe sepsis and septic shock 12 . Another study conducted in Brazil analyzed data from 75 ICU in different regions, and found mortality rates of 16.7% for sepsis, 34% for severe sepsis, and 65.3% for septic shock 13 . Overall mortality rates for sepsis have decreased, but, at 20% to 80%, are still unacceptably high 14 .…”

Section: Introductionmentioning

confidence: 99%

Sepse na unidade de terapia intensiva: etiologias, fatores prognósticos e mortalidade

Zanon¹,

Caovilla²,

Michel³

et al. 2008

Rev. bras. ter. intensiva

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SUMMARY BACKGROUND AND OBJECTIVES:Sepsis is the main cause of death in patients treated in intensive care units (ICU). The aim of this study was to evaluate etiology, prognostic factors and mortality of septic patients treated in ICU of Passo Fundo, Brazil. developed SIRS (58%). The most frequent cause of internation was neurological disease (28.9%), the most frequent site of infection was the respiratory tract (71.6%), and the most prevalent pathogens were gram-negative bacilli (53.2%). Mean APACHE II score was 18 ± 9, and mean SOFA score was 5 ± 4. Median ICU stay was 6 (3-11) days and overall mortality rate was 31.1%: 6.1% for non-infectious SIRS, 10.1% for sepsis, 22.6% for severe sepsis, and 64.8% for septic shock. CONCLUSIONS: Sepsis is an important health problem that leads to an extremely high mortality rate in the ICU of Passo Fundo, Brazil. METHODS:

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Section: Editorialmentioning

confidence: 99%

“…For instance, the mortality rate of patients in Brazil with septic shock is greater than 50%. (3)(4)(5) The reasons underlying such unfavorable outcomes are unclear; however, organizational issues and early detection are certainly important features in such an assessment.This issue of the Brazilian Journal of Intensive Care (Revista Brasileira de Terapia Intensiva -RBTI) includes an article that is crucial for a better understanding of the current status of sepsis and infections in critically ill patients. (6) This study performed a sub-analysis of EPIC II (Extended Prevalence of Infection in Intensive Care), which is a cross-sectional study that included 13,796 patients, more than 9,000 patients who received antimicrobial agents and approximately 7,000 patients who were diagnosed as infected.…”

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confidence: 99%

Prevalência e desfechos das infecções nas UTIs brasileiras: mais uma peça no quebra-cabeça...

Lisboa¹,

Póvoa²

2012

Rev. bras. ter. intensiva

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Infection prevalence and outcomes in BraziliansICUs: another brick in the wall.. Prevalência e desfechos das infecções nas UTIs brasileiras: mais uma peça no quebra-cabeça... EDITORIALInfections significantly influence the morbidity and mortality rates of intensive care units (ICUs), and the prevalence and impact of severe infections in critically ill patients have increased progressively in recent years. (1,2) In addition, more than 70% of critically ill patients admitted to ICUs are prescribed an antimicrobial agent during their stay. (1) Unfortunately, the actual situation in Brazil is difficult to assess because high-quality data on the local conditions are scarce in the literature. The few studies that sought to retrieve Brazilian data on infections and sepsis reported extremely important results, showing that both the prevalence and the lethality associated with infection in critically ill patients is high compared to the values reported in the international literature. For instance, the mortality rate of patients in Brazil with septic shock is greater than 50%. (3)(4)(5) The reasons underlying such unfavorable outcomes are unclear; however, organizational issues and early detection are certainly important features in such an assessment.This issue of the Brazilian Journal of Intensive Care (Revista Brasileira de Terapia Intensiva -RBTI) includes an article that is crucial for a better understanding of the current status of sepsis and infections in critically ill patients. (6) This study performed a sub-analysis of EPIC II (Extended Prevalence of Infection in Intensive Care), which is a cross-sectional study that included 13,796 patients, more than 9,000 patients who received antimicrobial agents and approximately 7,000 patients who were diagnosed as infected. The sub-analysis assessed only patients in Brazil and provides precise, high-quality data on the prevalence and characteristics of the patients admitted to Brazilian ICUs. More than 1,200 patients admitted to 90 ICUs across Brazil were included for analysis in this sub-analysis, which is currently the largest study of its type in the literature.Some data in the cross-sectional study are worth noting. Approximately 62% of the patients admitted to Brazilian ICUs presented with clinical evidence of infection; this prevalence is significantly higher than the prevalences reported by the same database for other areas, such as Europe and North America (where the prevalence is less than 50%). (1) In addition to higher prevalence, our ability to identify the etiology of infection is poor; thus, the pathogens that were potentially responsible for the infection were isolated in only 50% of the cases. The most frequent site of infection was the respiratory system (61%). The distribution of the pathogens associated with infection in Brazilian ICUs is also worth noting for several reasons. Brazil has a higher prevalence of Gram-negative agents compared to other

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Sepse Brasil: estudo epidemiológico da sepse em Unidades de Terapia Intensiva brasileiras

Cited by 91 publications

References 35 publications

Epidemiological profile of ICU patients at Faculdade de Medicina de Marília

Epidemiological profile of ICU patients at Faculdade de Medicina de Marília

Sepse na unidade de terapia intensiva: etiologias, fatores prognósticos e mortalidade

Prevalência e desfechos das infecções nas UTIs brasileiras: mais uma peça no quebra-cabeça...

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