Separation of vanillylmandelic (VMA) and homovanillic (HVA) acids from urine for assay by a two resin column system

Acidic metabolite profiling analysis of catecholamine and serotonin as O‐ethoxycarbonyl/tert‐butyldimethylsilyl derivatives by gas chromatography–mass spectrometry

“…Profiling analyses of CAs following conversion into volatile derivatives have involved capillary gas chromatography (GC) coupled with mass spectrometry (MS), owing to its advantages, including high resolution, sensitivity and positive peak confirmation. However, only a few results concerning acidic metabolites of catecholamine as CAs have been reported (Calvary et al, 1978;Kågedal and Goldstein, 1988;Loutelier-Bourhis et al, 2004;Muskiet et al, 1978;Narasimhachari et al, 1975;Nikolajsen and Hansen, 2001;Shimamura et al, 1986;van de Calseyde et al, 1971).…”