Separation of theophylline, caffeine and related drugs by normal-phase capillary electrochromatography

Lai, Edward P. C.; Da̧bek-Złotorzyńska, Ewa

doi:10.1002/(sici)1522-2683(19990801)20:12<2366::aid-elps2366>3.0.co;2-o

Cited by 33 publications

(2 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unfortunately, xanthine alkaloids with similar configurations cannot be separated and extracted easily by traditional separation and extraction methods. To date, there have been a few methods and techniques reported to quantitative extraction of TPE from its isomeride aqueous solution and plasma sample, 6–11 such as organic solvent (chloroform), 6 syringe-type minicolume of liquid chromatography, 7 capillary electro-chromatography, 8 a series of molecular imprinted based polymer, 9 film 10 and membrane. 11 But their limitations arise from low extraction capacity, long extraction time, high energy-consumption, complex operations, and toxicity of organic solvents, and so on.…”

Section: Introductionmentioning

confidence: 99%

Nanoscale zeolitic imidazolate framework-8 as a selective adsorbent for theophylline over caffeine and diprophylline

et al. 2014

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Nanoscale zeolitic imidazolate framework-8 as a selective adsorbent for theophylline over caffeine and diprophylline

et al. 2014

View full text Add to dashboard Cite

show abstract

“…A monolithic column with the mixed-mode of reversed-phase and anion-exchange has been developed for CEC separation of anilines in the "counterdirectional mode" [12]. An alternative was to use bare (unbounded) silica gel, since it has demonstrated successful applications in the analysis of basic drugs in HPLC and CEC [13][14][15][16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Electrochromatographic evaluation of a silica monolith capillary column for separation of basic pharmaceuticals

Xie

Xiao

et al. 2005

Electrophoresis

View full text Add to dashboard Cite

A silica-based monolithic capillary column was prepared via a sol-gel process. The continuous skeleton and large through-pore structure were characterized by scanning electron microscopy (SEM). The native silica monolith has been successfully employed in the electrochromatographic separation of b-blockers and alkaloids extracted from traditional Chinese medicines (TCMs). Column efficiencies greater than 250 000 plates/m for capillary electrochromatography (CEC) separation of basic compounds were obtained. It was observed that retention of basic pharmaceuticals on the silica monolith was mainly contributed by a cation-exchange mechanism. Other retention mechanisms including reversed-phase and normal-phase mechanisms and electrophoresis of basic compounds also played a role in separation. A comparison of the differences between CEC and capillary zone electrophoresis (CZE) separation was also discussed.

show abstract

Recent applications of capillary electrochromatography

et al. 2001

View full text Add to dashboard Cite

A review is presented of the most important recent applications of capillary electrochromatography (CEC) for the analysis of acidic, basic, and neutral compounds, of biomolecules, environmental substances, natural products, pharmaceuticals, and chiral compounds. Packed-column CEC (packed-CEC), open-tubular (OT-CEC), as well as pressure-assisted CEC (pseudo-CEC) are hereby considered. Papers published between July 1999 and April 2001 were taken into account. Applications before July 1999 have been reviewed in Electrophoresis 1999, 20, 3027-3065.

show abstract

Separation of theophylline, caffeine and related drugs by normal-phase capillary electrochromatography

Cited by 33 publications

References 27 publications

Nanoscale zeolitic imidazolate framework-8 as a selective adsorbent for theophylline over caffeine and diprophylline

Nanoscale zeolitic imidazolate framework-8 as a selective adsorbent for theophylline over caffeine and diprophylline

Electrochromatographic evaluation of a silica monolith capillary column for separation of basic pharmaceuticals

Recent applications of capillary electrochromatography

Contact Info

Product

Resources

About