2012
DOI: 10.1016/j.bej.2012.06.009
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Separation of phenylalanine and tyrosine by ion-exchange using a strong-base anionic resin. I. Breakthrough curves analysis

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Cited by 10 publications
(5 citation statements)
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“…This is because the least-adsorbed substance ethanol was displaced and desorbed simultaneously by the middle adsorbed one (acetic acid), whereas the most adsorbed component (acetoin) replaced acetic acid as well. According to Moreira and Ferreira, the overshoot phenomena in adsorption multicomponent systems as a result of the competition for active sites on the resin can be predicted by the equilibrium theory and considering the column divided into zones of unique compositions, called plateaus, separated from each other by zones of varying compositions, called transitions. The peaks in the concentrations during the breakthrough of ethanol and acetic acid occur at times of 96 and 107 min, respectively.…”
Section: Resultsmentioning
confidence: 99%
“…This is because the least-adsorbed substance ethanol was displaced and desorbed simultaneously by the middle adsorbed one (acetic acid), whereas the most adsorbed component (acetoin) replaced acetic acid as well. According to Moreira and Ferreira, the overshoot phenomena in adsorption multicomponent systems as a result of the competition for active sites on the resin can be predicted by the equilibrium theory and considering the column divided into zones of unique compositions, called plateaus, separated from each other by zones of varying compositions, called transitions. The peaks in the concentrations during the breakthrough of ethanol and acetic acid occur at times of 96 and 107 min, respectively.…”
Section: Resultsmentioning
confidence: 99%
“…An abundant literature describes the computation and simulation of chromatographic performance of beds of particles based on either purely mathematical or computational calculations [24][25][26][27][28]43]. Computational models are based on different classical schemes, generally propagation through a grid, or an integrated set of differential equations.…”
Section: Simulation Methods and Starting Hypothesismentioning
confidence: 99%
“…The simulation of radial diffusional effects in chromatographic columns has been undertaken. The focus of previous studies has been mainly on considering axial diffusion, in one-dimensional column models, because of its direct effect on peak broadening [24][25][26][27][28]. Some studies [29][30][31] examined the effect of a radial transfer phenomenon, heat transfer, on the efficiency of UHPLC columns.…”
Section: Introductionmentioning
confidence: 99%
“…The annual production of NaGA is estimated to be 2 million tons, which is nearly half of the total amino acid production [1][2][3]. A microbial fermentation method is typically used for its industrial production.…”
Section: Introductionmentioning
confidence: 99%