Separation of motile human sperms in a T-shaped sealed microchannel

Mane, Nikhil S.; Puri, Dhiraj B.; Mane, Sanjay; Hemadri, Vadıraj; Banerjee, Arnab; Tripathi, Siddhartha

doi:10.1007/s13534-022-00229-9

Cited by 10 publications

(4 citation statements)

References 47 publications

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“…Mane et al [278] proposed a T-shaped sealed microchannel to purify motile sperm cells (figure 15(c)). The motile sperm is separated progressively from the fluid flow at the zone near the 'T' junction.…”

Section: Biomedical Fieldmentioning

confidence: 99%

“…Reproduced from [277], with permission from Springer Nature. (c) T-shaped sealed microchannels for the separation of motile human sperms [278]. Reproduced from [278], with permission from Springer Nature.…”

Section: Capillaric Circuitsmentioning

confidence: 99%

“…(c) T-shaped sealed microchannels for the separation of motile human sperms [278]. Reproduced from [278], with permission from Springer Nature. (d) Chitosan scaffolds construction with microchannels for tissue engineering [279].…”

Section: Capillaric Circuitsmentioning

confidence: 99%

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Functional microfluidics: theory, microfabrication, and applications

Xie,

Zhan,

et al. 2024

Int. J. Extrem. Manuf.

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Microfluidic devices are composed of microchannels with a diameter ranging in ten to a few hundred micrometers. Thus, quite small (10-9 to 10-18 litres) amount of liquid can be manipulated by such a precise system. In the past three decades, significant progresses in materials, microfabrication, and various applications have boosted the development of promising functional microfluidic devices. In this review, the recent progresses on novel microfluidic devices with various functions and applications are presented. First, the theory and numerical methods for studying the performance of microfluidic devices are briefly introduced. Then, materials, and fabrication methods of functional microfluidic devices are summarized. Next, from the viewpoint of the applications of the microfluidic devices, the recent significant advances in heat sink, clean water production, chemical reactions, sensor, biomedical field, capillaric circuits, flexible and wearable electronic devices, microrobotics, etc., in turns are then highlighted. Finally, personal perspectives on the challenges and future developments of functional microfluidic devices, aiming to motivate researchers from the fields of engineering, materials, chemistry, mathematics, physics, etc. working together to promote further development and applications of functional microfluidic devices, for the specific purpose of carbon neutrality are provided.

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Section: Biomedical Fieldmentioning

confidence: 99%

Section: Capillaric Circuitsmentioning

confidence: 99%

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Functional microfluidics: theory, microfabrication, and applications

Xie,

Zhan,

et al. 2024

Int. J. Extrem. Manuf.

View full text Add to dashboard Cite

show abstract

“…32 Similarly, Mane et al used a T-junction design and created a rheotaxis zone by sealing one branch, collecting sperms showing rheotactic behavior. 33 The cervix and the uterotubal junction (UTJ) are also of particular importance due to their special structural characteristics and microenvironment that can regulate sperm passage through FRT. 34,35 One study, using a microfluidic platform as an in vitro model, concluded that the microgrooves in the bovine cervix, which is also present in humans, assist the passage of sperms through the cervix.…”

Section: Introductionmentioning

confidence: 99%