“…In contrast to the biological antibody, the substantial advantages of artificial counterparts are their mechanical and chemical stability, low cost of preparation and wide range of operating conditions. To date, MIP has been widely used in the fields of chromatographic separation, as antibody mimetics and artificial receptor, and catalysis (Matsui et al, 2007;Kempe and Mosbach, 1995;Yang et al, 2004;Ouyang et al, 2007;Tong et al, 2001;Ye and Mosbach, 2001;Bossi et al, 2001;Liu et al, 2011;Zeng et al, 2010). The majority of the MIP has been prepared using small molecules as template, much less attention has been paid to the protein recognition (Rusmini et al, 2007;Gale et al, 2009;Klepamik et al, 2011).…”