Separation mechanisms of citric and itaconic acids by water-immiscible amines

Bressler, Eyal; Braun, Sergei

doi:10.1002/(sici)1097-4660(199909)74:9<891::aid-jctb113>3.0.co;2-e

Cited by 24 publications

(24 citation statements)

References 16 publications

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“…Crystallization is the usual unit process for recovery of IA, relying on evaporation and cooling of the solution. Other recovery methods from aqueous solutions or fermented broths have been reported, such as liquid–liquid extraction − and membrane separations. − However, besides the work carried out by Gulicovski et al, little is described about IA recovery through adsorption.…”

Section: Introductionmentioning

confidence: 99%

Separation of Itaconic Acid from Aqueous Solution onto Ion-Exchange Resins

et al. 2015

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Itaconic acid (IA) is an unsaturated diacid, a promising compound that might replace part of the petrochemical-based monomers, such as acrylic acid, as a building block for polymers. Recent developments in biotechnology allow the efficient production of IA through fermentation processes. However, further enhancements are necessary in the downstream (recovery) of the product. This investigation examined the separation of IA by adsorption from aqueous solutions, using two types of commercial, strongly basic ion-exchange resins: Purolite A-500P and PFA-300. To evaluate the separation process, the following parameters were tested: pH (from 3.03 to 6.33), temperature (from 10 to 50 °C), and IA concentration (from 0.41 to 6.50 g·L–1). The Freundlich and Langmuir isotherms were shown to be good fits to the experimental data, and the adsorption kinetics for IA was found to follow a pseudo-second-order (PSO) model. After batch tests, continuous adsorption experiments were carried out using a fixed bed column, and a simplified mathematical model was developed and evaluated in order to determine the adsorption parameters. The experimental data obtained from the column tests were aligned with those obtained from the isotherms and batch simulations with PSO. The resin PFA-300 proved to be more efficient for IA recovery through adsorption, with a maximum capacity of 0.154 gIA.gresin –1 when compared to the resin A-500P, with a maximum capacity of 0.097 gIA.gresin –1. Both resins have high affinity for the solute, being half-saturated with equilibrium concentrations below 0.25 g·L–1 of acid.

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Section: Introductionmentioning

confidence: 99%

Separation of Itaconic Acid from Aqueous Solution onto Ion-Exchange Resins

et al. 2015

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“…This may indicate de novo synthesis of cis ‐aconitate decarboxylase and of other post‐citric stage enzymes of IA biosynthesis as suggested by Jaklitsch et al 7 and Bentley and Thiessen 3. Bonnarme et al 11 found that chloramphenicol (10–50 mg dm −3 ), an inhibitor of protein synthesis at the 70S ribosome, slightly increased IA yields from sugar substrate. Unexpectedly, 6‐azauracil (3 mg dm −3 ), an inhibitor of the fungal mRNA synthesis, increased both the IA accumulation rate and the maximal conversion yield.…”

Section: Resultsmentioning

confidence: 99%

“…The Reaction/Product SLM with the selectivity toward IA ( S IA/CA = 11.8) contained methyltrioctylamine and di‐(2‐ethylhexyl) phosphate (MTOA–DEHPA) 66 mmol dm −3 in dichloromethane (DCM). The mechanism of differential selectivity and other details concerning these SLMs are described elsewhere 6…”

Section: Methodsmentioning

confidence: 99%

Conversion of citric acid to itaconic acid in a novel liquid membrane bioreactor

Bressler

Braun

2000

J. Chem. Technol. Biotechnol.

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A novel liquid membrane reactor was designed to carry out the conversion of citric acid to itaconic (methylene succinic) acid by the fungus Aspergillus terreus. This bioreactor contained two supported liquid membranes (SLMs) that divided it into three compartments: (1) the feed chamber containing citric acid; (2) the reaction chamber containing the enzyme A terreus cells; and (3) the product collection chamber containing the counter-ion. The speci®city of SLMs allows the unidirectional¯ow, of the substrate from the feed to the reaction chamber, and of the product from the reaction to the product chamber in exchange for a counter-ion, thus maintaining low concentrations of both the product and the substrate, and limiting their inhibitory effects on the conversion process. The yield of itaconic acid in the membrane bioreactor was about two orders of magnitude higher than in the batch process.

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“…For this purpose, many different methods have been investigated in the literature to separate carboxylic acids from their aqueous solutions (5-7). Among these methods, membrane processes (8,9), electrodialysis processes (10,11), crystallization processes (12,13), and reactive extraction processes (14)(15)(16)(17)(18) have been used to remove itaconic acid from the aqueous solution. However, when these methods were compared with each other, it is possible to mention of various drawbacks.…”

Section: Introductionmentioning

confidence: 99%

Mg-Al Layered Double Hydroxide (LDH) as an Adsorbent for Removal of Itaconic Acid from Aqueous Solutions: Equilibrium and Kinetic Study

Lalikoğlu

2021

Journal of the Turkish Chemical Society Section A: Chemistry

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This study aims to remove itaconic acid, one of the important members of carboxylic acids, from its aqueous solutions by using an adsorption method. Recently the Layered Double Hydroxide (LDH), which has attracted attention in many areas, was synthesized by the co-precipitation method and used as an adsorbent. The effects of the adsorption time, LDH amounts, adsorption temperature, and initial acid concentration changes on the adsorption efficiency were examined. In one-stage batch adsorption experiments performed under different conditions, approximately 70% of itaconic acid was removed from the aqueous phase using 1 g of LDH. Various adsorption isotherm models such as Langmuir, Freundlich, and Temkin were applied to the obtained experimental data. Since R 2 values are greater than 0.98, it can be said that the experimental data fit all three isotherm models. Kinetic studies were carried out using timedependent measurements. Adsorption behavior was kinetically investigated using pseudo-first-order, pseudo-second-order, and Elovich models. The kinetics of the adsorption of itaconic acid by LDH was found to be the best defined by the pseudo-second-order model.

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Separation mechanisms of citric and itaconic acids by water-immiscible amines

Cited by 24 publications

References 16 publications

Separation of Itaconic Acid from Aqueous Solution onto Ion-Exchange Resins

Separation of Itaconic Acid from Aqueous Solution onto Ion-Exchange Resins

Conversion of citric acid to itaconic acid in a novel liquid membrane bioreactor

Mg-Al Layered Double Hydroxide (LDH) as an Adsorbent for Removal of Itaconic Acid from Aqueous Solutions: Equilibrium and Kinetic Study

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