Separation and identification of isomeric acidic degradation products of organophosphorus chemical warfare agents by capillary electrophoresis-ion trap mass spectrometry

Recent advances in CE and CEC separation, detection and sample preparation/preconcentration methodologies, for the determination of a variety of compounds having current or potential environmental relevance, have been overviewed. The reviewed literature has illustrated the wide range of CE applications available, indicating a continuing interest in CE and CEC in the environmental field. New developments in chip-based CE systems are also discussed.

Section: Explosives and Chemical Warfare Agent Residuesmentioning

confidence: 96%

Section: Explosives and Chemical Warfare Agent Residuesmentioning

confidence: 98%

Section: Advances In Detectionmentioning

confidence: 99%

See 1 more Smart Citation

Recent advances in CE and CEC of pollutants

Da̧bek-Złotorzyńska¹,

Celo²,

Yassine³

2007

“…[20]. Sonication with ACN, for example, was used by Groom et al Lagarrigue et al [25] have developed a method for the separation and identification of chemical warfare agent degradation products (five alkylphosphonic acids and five alkyl alkylphosphonic acids) by CE-IT-MS. The relevant instrumental parameters were optimised (Table 1) in order to improve CE selectivity and MS detection.…”

Section: Soils and Sedimentsmentioning

confidence: 99%

The application of CE‐MS in the trace analysis of environmental pollutants and food contaminants

Robledo

Smyth

2009

In this review, selected applications of CE-MS in recent years have been highlighted for the separation, detection and determination of environmental pollutants and food contaminants in selected samples. Trace analysis by CE-MS of analytes such as low molecular mass amines, nitroaromatics, alkylphosphonic acids, azo dyes, antidepressants, and antibiotic drugs, among others, in air, sediment and water samples have been reviewed. The CE-MS analysis of pesticides such as triazolopyrimidine sulphoanilides, different types of antibiotics (sulphonamides, beta-lactones, quinolones and tetracyclines) and other exogenous compounds such as acrylamide and toxic oligopeptides in food samples has also been reviewed. The review gives details on the fragmentations, where available, that the ionic species exhibit in-source and in ion trap, triple quadrupole and ToF MS analysers. A critical evaluation is also given of these recent CE-MS analytical methods for the separation, detection and determination of trace levels of such pollutants and contaminants with analytical information on the treatment of the samples, CE separation conditions, linearity ranges, LODs and recoveries from the different matrices presented.

“…Outside the field of drug analysis, CE-MS was also applied to the separation and identification of chemical warfare agent degradation products (alchylphosphonic acid and alchyl, alchyl phosphonic acid) in soil extracts [40].…”

Section: Forensic Drugs Toxicants and Dyesmentioning

confidence: 99%

Recent advances in the applications of CE to forensic sciences (2005–2007)

Tagliaro

Bortolotti

2007

The present article reviews the applications of CE in forensic science covering the period from 2005 until the first part of 2007. The overview includes the most relevant examples of analytical applications of capillary electrophoretic and electrokinetic techniques in the following fields: (i) forensic drugs, toxicants and dyes, (ii) small ions of forensic interest (iii) explosives, (iv) forensic DNA, and (v) other biopolymers of forensic interest.