Separation and detection of compounds in Honeysuckle by integration of ion-exchange chromatography fractionation with reversed-phase liquid chromatography-atmospheric pressure chemical ionization mass spectrometer and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis

Chen, Xueguo; Hu, Lianghai; Su, Xingye; Kong, Liang; Ye, Mingliang; Zou, Hanfa

doi:10.1016/j.jpba.2005.07.043

Cited by 36 publications

(5 citation statements)

References 28 publications

(34 reference statements)

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“…Other compounds detected in the extract have been described in different plants belonging to the Lamiaceae family, such as quinic acid, syringic acid, rosmarinic acid-3- O -glucoside, [ 9 ]-shogaol and the triterpenic acids asiatic, benthamic, and augustic acids [ 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 ]. The MS/MS analysis of rosmarinic acid-3- O -glucoside showed the major fragments at m / z 477, 359 and 323 corresponding to [M–H–COO] − , [M–H–C 6 H 10 O 5 ] − , and [M–H–C 9 H 10 O 5 ] − [ 52 ]. Lastly, two different isomers of [ 9 ]-shogaol were also characterized with the same fragmentation patterns, possessing two fragment ions for [M–H–OCH 3 ] − and [M–H–C 10 H 19 ] − ( m / z 287 and 179, respectively).…”

Section: Resultsmentioning

confidence: 99%

Rosmarinus Officinalis Leaves as a Natural Source of Bioactive Compounds

Borrás-Linares

Stojanović

Quirantes-Piné

et al. 2014

IJMS

175

139

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In an extensive search for bioactive compounds from plant sources, the composition of different extracts of rosemary leaves collected from different geographical zones of Serbia was studied. The qualitative and quantitative characterization of 20 rosemary (Rosmarinus officinalis) samples, obtained by microwave-assisted extraction (MAE), was determined by high performance liquid chromatography coupled to electrospray quadrupole-time of flight mass spectrometry (HPLC–ESI-QTOF-MS). The high mass accuracy and true isotopic pattern in both MS and MS/MS spectra provided by the QTOF-MS analyzer enabled the characterization of a wide range of phenolic compounds in the extracts, including flavonoids, phenolic diterpenes and abietan-type triterpenoids, among others. According to the data compiled, rosemary samples from Sokobanja presented the highest levels in flavonoids and other compounds such as carnosol, rosmaridiphenol, rosmadial, rosmarinic acid, and carnosic acid. On the other hand, higher contents in triterpenes were found in the extracts of rosemary from Gložan (Vojvodina).

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Section: Resultsmentioning

confidence: 99%

Rosmarinus Officinalis Leaves as a Natural Source of Bioactive Compounds

Borrás-Linares

Stojanović

Quirantes-Piné

et al. 2014

IJMS

175

139

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“…Oxidized carbon nanotubes have been reported to give better results than carbon nanotubes themselves because of their greater solubility in water (Pan et al, 2005). They have been used to record MALDI spectra from honeysuckle constituents (Chen et al, 2006c). Schulz et al (2006) have compared the degree of analyte fragmentation in AP-MALDI as a function of the matrix and laser fluence.…”

Section: B Simple Matricesmentioning

confidence: 99%

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for the period 2005–2006

Harvey

2010

Mass Spectrometry Reviews

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This review is the fourth update of the original review, published in 1999, on the application of MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2006. The review covers fundamental studies, fragmentation of carbohydrate ions, method developments, and applications of the technique to the analysis of different types of carbohydrate. Specific compound classes that are covered include carbohydrate polymers from plants, N- and O-linked glycans from glycoproteins, glycated proteins, glycolipids from bacteria, glycosides, and various other natural products. There is a short section on the use of MALDI-TOF mass spectrometry for the study of enzymes involved in glycan processing, a section on industrial processes, particularly the development of biopharmaceuticals and a section on the use of MALDI-MS to monitor products of chemical synthesis of carbohydrates. Large carbohydrate-protein complexes and glycodendrimers are highlighted in this final section.

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“…Comprehensive 2-D chromatography has been widely used to characterize and separate complex mixtures due to its high peak capacity, powerful separation and high resolution [99][100][101][102]. On the basis of 2-D separation, Chen and Hu et al established a comprehensive 2-D liquid chromatographic separation system for TCM analysis [103][104][105][106]. Furthermore, 2-D liquid chromatography with biochromatography and conventional HPLC was established to improve the peak capacity and resolution of BFA.…”

Section: Screening and Analysis Of Bioactive Compounds By 2-d Biochromentioning

confidence: 99%

Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis

Kong²,

Zou³

et al. 2010

CCHTS

Self Cite

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Traditional Chinese medicines (TCMs), a key branch of natural medicines, play an important role in treatment of diseases because of their reliable clinical performance. Identification of their active compounds constitutes a bottleneck in the development of TCMs. Screening and analysis of active compounds is a challenge in TCMs research. This review summarizes recent progress in the development of biological fingerprinting strategies for screening and analyzing of bioactive compounds in TCMs using molecular recognition, metabolism and omics tools.The evaluated strategies including the following techniques: microdialysis/centrifugal ultrafiltration-HPLC, biochromatography, metabolic fingerprinting analysis, 2-dimensional biochromatography and omics fingerprinting analysis.

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Cited by 36 publications

References 28 publications

Rosmarinus Officinalis Leaves as a Natural Source of Bioactive Compounds

Rosmarinus Officinalis Leaves as a Natural Source of Bioactive Compounds

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for the period 2005–2006

Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis

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