Separación de componentes química (toxina botulínica tipo A) en la reparación de hernia ventral planeada: un modelo murino

Rodríguez-Ruiz, Gabriela; Chama-Naranjo, Alfredo; Oña-Ortiz, Flora Mileva; García-Arrona, Luis Roberto; Sánchez-Valle, Arturo A.; Chávez-Villanueva, Ulises; Mata-Quintero, Carlos Javier; Luna-Martínez, Javier

doi:10.1016/j.rehah.2015.04.002

Cited by 7 publications

(5 citation statements)

References 13 publications

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“…Cabe destacar que en 13 casos se aplicó también, junto al neumoperitoneo, toxina botulínica para relajar la musculatura abdominal. Puede deducirse que ambas técnicas se complementan y proporcionan beneficios en ambos casos, pues también se ha defendido el uso de TBA y ya se ha empleado debido a sus buenos resultados en grandes defectos herniarios 6,15 .…”

Section: Discussionunclassified

“…La incidencia de eventraciones es de un 13-20 % en pacientes con laparotomía previa 6,7 , sobre todo en los 3 años siguientes a la cirugía.…”

Section: Introductionunclassified

“…Constituyen un reto en cuanto a su reparación, pues el 30 % de las eventraciones reparadas sin material protésico recidivan debido, sobre todo, a la elevada tensión intraabdominal que se genera 6 . En su tratamiento se persigue la aproximación de las estructuras musculares sin tensión.…”

Section: Introductionunclassified

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Preoperative pneumoperitoneum in the surgical preparation of complex eventrations

Vigil¹,

Dueñas²,

Bastante³

et al. 2021

Rev Hispanoam Hernia

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Section: Discussionunclassified

“…La incidencia de eventraciones es de un 13-20 % en pacientes con laparotomía previa 6,7 , sobre todo en los 3 años siguientes a la cirugía.…”

Section: Introductionunclassified

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Preoperative pneumoperitoneum in the surgical preparation of complex eventrations

Vigil¹,

Dueñas²,

Bastante³

et al. 2021

Rev Hispanoam Hernia

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“…In the context of ventral hernia repair, muscle relaxation facilitates the apposition of defect edges without compromising the fascial integrity of the abdominal wall. This minimizes lateral muscle traction, subsequently reducing the need for manipulation and traction during surgical repair and decreasing the post-procedural analgesic requirement [11,12,[14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Effective Management of Giant Ventral Hernias: A Comprehensive Approach Combining Preoperative Botulinum Toxin Application, Modified Ramírez’s Component Separation, and Rives-Stoppa Hernioplasty

Serafio-Gómez,

Aragón-Quintana,

Bustillos-Ponce

et al. 2023

Cureus

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IntroductionGiant ventral hernias are a surgical challenge due to their size and the need for a specialized approach during repair. Over the decades, abdominal wall surgery has evolved into a sophisticated field with a wide range of techniques aimed at improving patient outcomes. However, there is no universally accepted method suitable for repairing all giant ventral hernias. Surgeons must rely on a combination of techniques, choosing the approach that best matches their expertise, available resources, and the individual patient's specific needs. This article explores the effective use of a combination of techniques, including preoperative botulinum toxin application, modified Ramírez's component separation, and Rives-Stoppa hernioplasty, yielding excellent results and minimizing recurrences. ObjectiveThis study aims to provide a comprehensive literature review of giant ventral hernias. Additionally, we aim to share our experience in managing and repairing giant ventral hernias using a multi-modal approach, combining various surgical techniques with a focus on patient safety, reduced recurrence rates, and improved quality of life. MethodsBetween October 1, 2019, and October 1, 2021, six patients with giant ventral hernias were enrolled at our department of surgery. They received preoperative botulinum toxin A (BT) application, underwent corrective surgery involving modified component separation following the Ramírez method, and received Rives-Stoppa hernioplasty. Follow-up was conducted for at least six months. ResultsSix patients were included in the study: three women and three men. They had an average age of 53.6 years and an average body mass index of 31.8 kg/m 2 . The most common location of the hernia defect was supra and infraumbilical, among 66% of cases. The primary adverse effect associated with BT application was abdominal distension, reported in 33% of patients. No postoperative complications, such as abscesses or seromas, were observed. After the surgical procedure, the average hospital stay was 2.6 days, and no recurrences were noted within six months post-surgery. ConclusionThe proposed method, which involves a combination of techniques, has demonstrated promising results based on our experience. However, to solidify these findings and better understand the full scope of this approach, further comprehensive statistical studies involving larger populations are essential. These studies will not only validate our results but also provide valuable insights for optimizing the management of giant ventral hernias.

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“…It has been described to have a safe profile when administered in remote areas of vital organs. In biological models, it has been shown to induce a decrease in intraabdominal pressure when administered in the preoperative time, facilitating closure of the hernial defect without the need to resort to the component separation technique [7] . In human studies, temporal paralysis of the lateral muscles has been found to allow primary fascial closure, with an adequate effectiveness, efficiency, and safety profile [6,8,9] .…”

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confidence: 99%

Botulinum toxin A in abdominal wall reconstruction for incisional hernia: an interesting line of research in abdominal wall and plastic surgery

Lozada-Martínez

Zgieb

Casas

et al. 2022

International Journal of Surgery: Global Health

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Separación de componentes química (toxina botulínica tipo A) en la reparación de hernia ventral planeada: un modelo murino

Cited by 7 publications

References 13 publications

Preoperative pneumoperitoneum in the surgical preparation of complex eventrations

Preoperative pneumoperitoneum in the surgical preparation of complex eventrations

Effective Management of Giant Ventral Hernias: A Comprehensive Approach Combining Preoperative Botulinum Toxin Application, Modified Ramírez’s Component Separation, and Rives-Stoppa Hernioplasty

Botulinum toxin A in abdominal wall reconstruction for incisional hernia: an interesting line of research in abdominal wall and plastic surgery

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